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Merck
모든 사진(2)

문서

MAB1293

Sigma-Aldrich

Anti-DNA Antibody, double stranded, clone AE-2

clone AE-2, Chemicon®, from mouse

동의어(들):

Double-stranded DNA antibody

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

AE-2, monoclonal

종 반응성(상동성에 의해 예측)

all

제조업체/상표

Chemicon®

기술

immunocytochemistry: suitable
immunohistochemistry: suitable

동형

IgG3

배송 상태

wet ice

타겟 번역 후 변형

unmodified

특이성

Double stranded DNA. MAB1293 produces a homogeneous staining pattern in the nucleus of normal and malignant cells.

면역원

Epitope: double stranded
Nuclei of Raji Burkitt′s lymphoma cells

애플리케이션

Anti-DNA Antibody, double stranded, clone AE-2 is a high quality Mouse Monoclonal Antibody for the detection of DNA & has been validated in ICC & IHC.
Immunocytochemistry: paraformaldehyde fixed cell preparations

Immunohistochemistry: paraformaldehyde fixed frozen tissue sections

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected double stranded DNA in human prostrate and tonsil tissue sections.

Optimal working dilutions must be determined by the end user.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

물리적 형태

Format: Purified
Purified immunoglobulin. Liquid in 0.02M Phosphate buffer with 0.25 NaCl and 0.1% sodium azide.

저장 및 안정성

Maintain at 2-8°C in undiluted aliquots for up to 6 months.

분석 메모

Control
POSITIVE CONTROL: Human tonsil

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Manuel Adrian Suter et al.
Scientific reports, 11(1), 7243-7243 (2021-04-02)
Deficiencies in DNA repair and DNA degrading nucleases lead to accumulation of cytosolic DNA. cGAS is a critical DNA sensor for the detection of cytosolic DNA and subsequent activation of the STING signaling pathway. Here, we show that the cGAS-STING
Yang Liu et al.
Scientific reports, 6, 18696-18696 (2016-01-05)
Iridovirid infection is associated with the catastrophic loss in aquaculture industry and the population decline of wild amphibians and reptiles, but none of the iridovirid life cycles have been well explored. Here, we report the detailed visualization of the life
Lateral elements inside synaptonemal complex-like polycomplexes in ndt80 mutants of yeast bind DNA.
Bhuiyan, H; Dahlfors, G; Schmekel, K
Genetics null
Sangita Khatri et al.
Journal of translational autoimmunity, 3, 100068-100068 (2020-11-19)
Neuropsychiatric systemic lupus erythematosus is an autoimmune disorder characterized by an irregular exchange between the central nervous system and the immune system, leading to the outbreak of neurological conditions with possible disabling effects. Although neuropsychiatric systemic lupus erythematosus is the
Xuan Song et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 41(45), 9286-9307 (2021-10-02)
Adult-onset neurodegenerative diseases are often accompanied by evidence of a chronic inflammation that includes activation of microglial cells and altered levels of brain cytokines. Aspects of this response are likely secondary reactions to neurodegeneration, but for many illnesses the inflammation

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