추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
5B11, monoclonal
종 반응성
human
제조업체/상표
Chemicon®
기술
ELISA: suitable
immunofluorescence: suitable
immunoprecipitation (IP): suitable
western blot: suitable
동형
IgG2a
배송 상태
wet ice
일반 설명
The Early Restricted protein (Ea-R) of Epstein-Bar Virus is encoded by the viral BHFR1 gene. Ea-R is a 17 kDa protein (p17) with protein kinase activity. Ea-R-p17 is a functional homologue of the anti-apoptotic oncoprotein bcl-2, which is expressed during the switch from latency to lytic replication and may be involved in proliferation of EBV infected cells. However, Ea-R-p17 does not appear to be essential for virus replication or transformation of B cells in vitro.
특이성
Recognizes the 17 kDa Early Restricted Protein (Ea-R-p17) of Epstein-Barr Virus by immunoblot, immunoprecipitation and immunofluorescence.
애플리케이션
Anti-EBV EA-R-p17 Antibody, clone 5B11 is an antibody against EBV EA-R-p17 for use in ELISA, IF, IP & WB.
Immunoblotting
Immunoprecipitation
Immunofluorescence
Optimal dilutions must be determined by the end user.
Immunoprecipitation
Immunofluorescence
Optimal dilutions must be determined by the end user.
Research Category
Infectious Diseases
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
Infectious Diseases - Viral
물리적 형태
Format: Purified
Purified immunoglobulin presented as a liquid in 0.02M PBS, 0.25M NaCl, with 0.1% sodium azide.
저장 및 안정성
Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Mingxia Shi et al.
Virus research, 177(1), 11-21 (2013-07-31)
Transition of Akata Burkitt's lymphoma (BL) from a malignant to nonmalignant phenotype upon loss of Epstein-Barr virus (EBV) is evidence for a viral contribution to tumorigenesis despite the tight restriction of EBV gene expression in BL. Examination of global cellular
Comparative analysis of the expression of the Epstein-Barr virus (EBV) anti-apoptotic gene BHRF1 in nasopharyngeal carcinoma and EBV-related lymphoid diseases
Nicholls, J. et al.
Journal of Medical Virology, 65, 105-113 (2001)
Functional differences between BHRF1, the Epstein-Barr virus-encoded Bcl-2 homologue, and Bcl-2 in human epithelial cells
Dawson, C. et al.
Journal of virology, 72, 9016-9024 (1998)
C A Meseda et al.
The Journal of general virology, 81(Pt 7), 1801-1805 (2000-06-22)
The human tumour virus Epstein-Barr virus (EBV) encodes a 17 kDa protein, BHRF1, which is a member of the BCL:-2 family and has been shown to suppress apoptosis. The role of this gene in the life-cycle of EBV has not
Identification of an Epstein-Barr virus early gene encoding a second component of the restricted early antigen complex
Pearson, G. et al.
Virology Journal, 160, 151-161 (1987)
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