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Merck
모든 사진(3)

주요 문서

MAB979

Sigma-Aldrich

Anti-Enterovirus 71 Antibody, cross-reacts with Coxsackie A16, clone 422-8D-4C-4D

ascites fluid, clone 422-8D-4C-4D, Chemicon®

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

항체 형태

ascites fluid

클론

422-8D-4C-4D, monoclonal

종 반응성

human

제조업체/상표

Chemicon®

기술

immunofluorescence: suitable

동형

IgG1

배송 상태

wet ice

특이성

Reacts with Enterovirus 71. Neutralizes enterovirus 71 BrCr strain at a titer of less than 1:14.

면역원

Epitope: cross-reacts with Coxsackie A16

애플리케이션

Indirect immunofluorescence at 1:1,000.

(Also cross-reacts with Coxsackie A16).

Optimal working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
This Anti-Enterovirus 71 Antibody, cross-reacts with Coxsackie A16, clone 422-8D-4C-4D is validated for use in IF for the detection of Enterovirus 71.

물리적 형태

Ascites fluid containing no preservatives.
Unpurified

저장 및 안정성

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

분석 메모

Control
Enterovirus Control Slides, Catalogue Number 5066

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Immunological and biochemical characterization of coxsackie virus A16 viral particles.
Chong, P; Guo, MS; Lin, FH; Hsiao, KN; Weng, SY; Chou, AH; Wang, JR; Hsieh, SY; Su, IJ; Liu, CC
Testing null
Rei-Lin Kuo et al.
PloS one, 8(5), e63431-e63431 (2013-05-08)
Induction of type-I interferons (IFNs), IFN-α/β, is crucial to innate immunity against RNA virus infection. Cytoplasmic retinoic acid-inducible gene I (RIG-I)-like receptors, including RIG-I and melanoma differentiation-associated gene 5 (MDA5), are critical pathogen sensors for activation of type-I IFN expression
Kan Xing Wu et al.
Nature communications, 7, 13150-13150 (2016-10-18)
Enterovirus 71 (EV71) is a neurotropic enterovirus without antivirals or vaccine, and its host-pathogen interactions remain poorly understood. Here we use a human genome-wide RNAi screen to identify 256 host factors involved in EV71 replication in human rhabdomyosarcoma cells. Enrichment
Elizabeth A Caine et al.
Journal of virology, 90(19), 8592-8604 (2016-07-22)
Hand, foot, and mouth disease (HFMD) has spread throughout the Asia-Pacific region, affecting millions of young children, who develop symptoms ranging from painful blisters around their mouths and hands to neurological complications. Many members of the genus Enterovirus (family Picornaviridae)
Combining multiplex reverse transcription-PCR and a diagnostic microarray to detect and differentiate enterovirus 71 and coxsackievirus A16.
Chen, Tsan-Chi, et al.
Journal of Clinical Microbiology, 44, 2212-2219 (2006)

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