추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
16B9.1, monoclonal
종 반응성
rat, human
기술
immunohistochemistry: suitable
western blot: suitable
동형
IgMκ
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... S1PR4(8698)
일반 설명
Sphingosine 1-phosphate receptor 4 (S1PR4), otherwise known as EDG6, is present, in varying expression levels, in the adult lymph node, bone marrow, and thymus, as well as fetal liver, lung, and thymus. It is activated by the lysosphingolipid sphingosine 1-phosphate, and is coupled to Gi and G12/13 G proteins and via their various effector molecules, SIP4 regulates cell proliferation, differentiation, motility, and migration.
면역원
GST-tagged recombinant protein corresponding to human S1PR4/EDG6.
애플리케이션
Detect S1PR4/EDG6 using this Anti-S1PR4/EDG6 Antibody, clone 16B9.1 validated for use in Western Blotting & IHC.
Immunohistochemistry Analysis: A 1:300 dilution from a representative lot detected S1PR4/EDG6 in human red bone marrow and human tonsil tissues.
품질
Evaluated by Western Blot Analysis in rat spleen tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected S1PR4/EDG6 in 10 µg of rat spleen tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected S1PR4/EDG6 in 10 µg of rat spleen tissue lysate.
표적 설명
~42 kDa observed
물리적 형태
Format: Purified
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
적합한 제품을 찾을 수 없으신가요?
당사의 제품 선택기 도구.을(를) 시도해 보세요.
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
The FEBS journal, 281(12), 2861-2870 (2014-05-07)
It has been reported that the effect of inflammatory cytokines on β-cell destruction in type 1 diabetes is concentration-dependent. However, the underlying mechanisms remain unclear. In the present study, we found that a high concentration of cytokines promoted apoptosis in
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 32(8), 1313-1322 (2017-02-17)
C5a plays a crucial role in anti-neutrophil cytoplasmic antibody (ANCA)-mediated neutrophil recruitment and activation. Our previous studies found that the interaction between sphingosine-1-phosphate (S1P) and C5a plays an important role in the ANCA-mediated activation of neutrophils. In the current study
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.