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Merck
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07964

Sigma-Aldrich

Methoxypolyethylene glycol amine

750

동의어(들):

mPEG-NH2, O-(2-Aminoethyl)-O′-methylpolyethylene glycol, Aminopolyethylene glycol monomethyl ether, Methoxypolyoxyethylene amine

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About This Item

Linear Formula:
H2NCH2CH2(OCH2CH2)nOCH3
CAS Number:
80506-64-5
MDL number:
MFCD00131599
UNSPSC 코드:
12162002
NACRES:
NA.22

Quality Level

100

형태

solid

색상

white to yellow

InChI

1S/C3H9NO/c1-5-3-2-4/h2-4H2,1H3

InChI key

ASUDFOJKTJLAIK-UHFFFAOYSA-N

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애플리케이션

Methoxypolyethylene glycol amine can:
  • Form dendritic micelles to enhance the solubility of hydrophobic compounds.
  • Conjugate with an anticancer drug methotrexate (MTX) to form MTX-PEG with potential application as drug carriers.
  • Couple with polyethylenimine (PEI) to form graft copolymers which can be used as nonviral gene vectors.

기타 정보

Oligomer used to prepare PEG-ylated conjugates having the advantage of reduced immunogenicity and increased serum half life

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

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시험 성적서(COA)

Lot/Batch Number
BCCK3989
BCCF9088
BCCC1456
BCBW2081
BCBT3891

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Polyethylene glycol-polyamidoamine dendritic micelle as solubility enhancer and the effect of the length of polyethylene glycol arms on the solubility of pyrene in water.
Yang H, et al.
Journal of Colloid and Interface Science, 273(1), 148-154 (2004)
Polyethylene Glycol Conjugates of Methotrexate Varying in Their Molecular Weight from MW 750 to MW 40000: Synthesis, Characterization, and Structure- Activity Relationships in Vitro and in Vivo.
Riebeseel K, et al.
Bioconjugate Chemistry, 13(4), 773-785 (2002)
T.P. Kogan
Synthetic Communications, 22, 2417-2417 (1992)
Effect of polyethylene glycol on gene delivery of polyethylenimine.
Sung SJ, et al.
Biological & Pharmaceutical Bulletin, 26(4), 492-500 (2003)
M Yokoyama et al.
Bioconjugate chemistry, 3(4), 295-301 (1992-07-01)
Adriamycin, a hydrophobic anticancer drug, was conjugated with poly(ethylene oxide)-poly(aspartic acid) block copolymers composed of various lengths of each block copolymer segment ranging from 1000 to 12,000 in molecular weight and from 10 to 80 units, respectively. Conjugation was achieved

문서

Fouling Resistant PEG Based Grafted Polymer Coatings

Biofouling control essential for device performance and safety; minimize accumulation of biomolecules and bioorganisms.

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