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202495

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Poly(ethylene glycol) methyl ether

average Mn 750

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Synonym(s):
Methoxy poly(ethylene glycol), Polyethylene glycol monomethyl ether, mPEG
Linear Formula:
CH3(OCH2CH2)nOH
CAS Number:
MDL number:
PubChem Substance ID:

vapor density

>1 (vs air)

Quality Level

vapor pressure

0.05 mmHg ( 20 °C)

form

paste
solid

mol wt

average Mn 750

refractive index

n20/D 1.459

viscosity

10.5 cSt(210 °F)(lit.)

transition temp

Tm 30 °C

density

1.094 g/mL at 25 °C

Ω-end

hydroxyl

α-end

methoxy

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI key

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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This Item
202509M6768202487
mol wt

average Mn 750

mol wt

average Mn ~2,000

mol wt

average mol wt 350

mol wt

average Mn 550

transition temp

Tm 30 °C

transition temp

Tm 52 °C

transition temp

-

transition temp

Tm 20 °C

density

1.094 g/mL at 25 °C

density

-

density

-

density

1.089 g/mL at 25 °C

Ω-end

hydroxyl

Ω-end

-

Ω-end

-

Ω-end

hydroxyl

α-end

methoxy

α-end

-

α-end

-

α-end

methoxy

Application

Poly(ethylene glycol) methyl ether can be used:
  • As a chain transfer agent to synthesize amphiphilic block copolymers by metal-free ring-opening oligomerization.
  • As a precursor to prepare retinoic acid-polyethylene glycol nanoassembly as an efficient drug delivery system.
  • To prepare diblock copolymer with polylactic acid, which can be applied in the field of tissue engineering and drug delivery.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

359.6 °F - closed cup

Flash Point(C)

182 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Articles

Accumulation of biological matter at surfaces is an inevitable event in virtually any environment in which natural and man-made materials are used. Although sometimes fouling of surfaces with biomolecules and bioorganisms has little consequence, biofouling must be minimized or controlled in order to maintain performance and safety of devices and structures.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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