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81323

Sigma-Aldrich

Poly(ethylene glycol) methyl ether

average MN 5,000, methoxy, hydroxyl

Synonym(s):

Polyethylene glycol, Methoxy poly(ethylene glycol), Polyethylene glycol monomethyl ether, mPEG

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About This Item

Linear Formula:
CH3(OCH2CH2)nOH
CAS Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

product name

Poly(ethylene glycol) methyl ether, average Mn 5,000

vapor density

>1 (vs air)

vapor pressure

0.05 mmHg ( 20 °C)

form

flakes
powder or crystals

mol wt

average Mn 5,000

mp

60-64 °C

Ω-end

hydroxyl

α-end

methoxy

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI key

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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Application

Poly(ethylene glycol) methyl ether (mPEG) is a hydrophilic polymer that is used to control the flexibility of a composite. mPEG can be used for a variety of applications such as drug delivery, tissue engineering, and other biological uses.

Other Notes

Polymer used in the polymer-supported liquid synthesis of oligosaccharides

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

359.6 °F - closed cup

flash_point_c

182 °C - closed cup

ppe

Eyeshields, Gloves


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Magnetite nanoparticles stabilized with polymeric bilayer of poly (ethylene glycol) methyl ether-poly (?-caprolactone) copolymers
Meerod S, et al.
Polymer, 49(18), 3950-3956 (2008)
S.P. Douglas et al.
Journal of the American Chemical Society, 113, 5095-5095 (1991)
Synthesis and characterization of triblock copolymers of methoxy poly (ethylene glycol) and poly (propylene fumarate)
Behravesh E, et al.
Biomacromolecules, 3(1), 153-158 (2002)
Hamed Nosrati et al.
Pharmaceutical development and technology, 24(1), 89-98 (2018-01-09)
In this study, we designed a polymersome system for the controlled release of methotrexate (MTX) as an anticancer drug with the objective of improving the loading efficiency of the drug in polymersomes as well as achievement of an efficient control
Kangan Li et al.
International journal of nanomedicine, 8, 2589-2600 (2013-07-28)
Development of dual-mode or multi-mode imaging contrast agents is important for accurate and self-confirmatory diagnosis of cancer. We report a new multifunctional, dendrimer-based gold nanoparticle (AuNP) as a dual-modality contrast agent for magnetic resonance (MR)/computed tomography (CT) imaging of breast

Articles

Biofouling control essential for device performance and safety; minimize accumulation of biomolecules and bioorganisms.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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