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O-(2-Aminoethyl)polyethylene glycol 3,000

Mp 3,000

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Synonym(s):
Aminopolyethylene glycol
Linear Formula:
NH2(CH2CH2O)nH
CAS Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

mol wt

Mp 3,000

Quality Level

reaction suitability

reagent type: cross-linking reagent

Ω-end

hydroxyl

α-end

amine

SMILES string

[H]OCCN

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This Item
67213067192470023
reaction suitability

reagent type: cross-linking reagent

reaction suitability

-

reaction suitability

-

reaction suitability

reagent type: cross-linking reagent

Ω-end

hydroxyl

Ω-end

hydroxyl

Ω-end

hydroxyl

Ω-end

-

α-end

amine

α-end

amine

α-end

amine

α-end

-

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

General description

O-(2-Aminoethyl)polyethylene glycol is a heterobifunctional polyethylene glycol (hydroxyl-PEG-amine) useful in conjugation and crosslinking reactions.

Application

O-(2-Aminoethyl)polyethylene glycol has been used to synthesize PEG-poly(D,L-lactide-co-glycolide) (PEG-PLGA) conjugate for use in the synthesis of PLGA-based nanoparticles.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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