26454

Magnesium stearate

puriss., meets analytical specification of Ph. Eur., BP, ≥90% stearic and palmitic acid basis, ≥40% stearic acid basis (GC), 4.0-5.0% Mg basis (calc on dry sub.)

• 동의어(들): Stearic acid magnesium salt
• Linear Formula: [CH₃(CH₂)₁₆CO₂]₂Mg
• CAS Number: 557-04-0
• Molecular Weight: 591.24
• Beilstein: 3919702
• EC Number: 209-150-3
• MDL number: MFCD00036391
• UNSPSC 코드: 12352106
• PubChem Substance ID: 57648176
• NACRES: NA.22

속성

• grade: puriss.
• 분석: ≥40% stearic acid basis (GC); ≥90% stearic and palmitic acid basis; 4.0-5.0% Mg basis (calc on dry sub.)
• 품질: meets analytical specification of Ph. Eur., BP
• 불순물: acidity or alkalinity, complies; microbiological impurity, in accordance; residual solvents, complies
• 손실: ≤6.0% loss on drying, 105 °C
• mp: 200 °C (lit.)
• 산성 값: 195‑210(fatty acid)
• solubility: alcohol: insoluble; diethyl ether: insoluble; water: insoluble
• 음이온 미량물: chloride (Cl^-): ≤1000 mg/kg; sulfate (SO₄^2-): ≤5000 mg/kg
• 양이온 미량물: Cd: ≤3 mg/kg; Ni: ≤5 mg/kg; Pb: ≤10 mg/kg
• 적합성: in accordance for fatty acid composition; passes test for identity
• 응용 분야: pharmaceutical (small molecule)
• SMILES string: CCCCCCCCCCCCCCCCCC(=O)O[Mg]OC(=O)CCCCCCCCCCCCCCCCC
• InChI: 1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
• InChI key: HQKMJHAJHXVSDF-UHFFFAOYSA-L

설명

애플리케이션

Magnesium stearate has been used as a tablet and capsule lubricant. It has also been used for preparing microcapsules.

생화학적/생리학적 작용

Magnesium stearate is the magnesium salt of stearic acid that possess lubricating properties and hence prevents ingredients from sticking to manufacturing equipment during the compression of chemical powders into solid tablets. Dry coating of drugs with magnesium stearate leads to flow improvement, flow-aid and lubrication effects, tabletability as well as non-inhibited dissolution rate.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves