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Merck
모든 사진(2)

주요 문서

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32103

Supelco

Posaconazole

VETRANAL®, analytical standard

동의어(들):

4-[4-[4-[4-[[(3R,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one

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모든 사진(2)

About This Item

실험식(Hill 표기법):
C37H42F2N8O4
CAS Number:
171228-49-2
Molecular Weight:
700.78
MDL number:
MFCD00941162
UNSPSC 코드:
41116107
PubChem Substance ID:
329753992
NACRES:
NA.24

Grade

analytical standard

Quality Level

100

제품 라인

VETRANAL®

유통기한

limited shelf life, expiry date on the label

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

clinical testing

형식

neat

SMILES string

CC[C@@H]([C@H](C)O)N1N=CN(C1=O)c2ccc(cc2)N3CCN(CC3)c4ccc(OC[C@@H]5CO[C@@](C5)(Cn6cncn6)c7ccc(F)cc7F)cc4

InChI

1S/C37H42F2N8O4/c1-3-35(26(2)48)47-36(49)46(25-42-47)31-7-5-29(6-8-31)43-14-16-44(17-15-43)30-9-11-32(12-10-30)50-20-27-19-37(51-21-27,22-45-24-40-23-41-45)33-13-4-28(38)18-34(33)39/h4-13,18,23-27,35,48H,3,14-17,19-22H2,1-2H3/t26-,27+,35-,37-/m0/s1

InChI key

RAGOYPUPXAKGKH-XAKZXMRKSA-N

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일반 설명

Posaconazole is an azole antifungal drug used mostly against zygomycetes.

애플리케이션

Posaconazole may have been used as reference standard in HPLC analysis for quantification of posaconazole from human plasma.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

법적 정보

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
BCCK0662
BCCH9785
BCCC8920
BCCB7317
BCBT7167

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

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문서 라이브러리 방문

Posaconazole as salvage therapy for zygomycosis.
Greenberg, R. N., et al.
Antimicrobial Agents and Chemotherapy, 50.1, 126-133 (2006)
Shu-Ying Yu et al.
Infection and drug resistance, 11, 1537-1547 (2018-10-06)
Trichosporon dohaense is a rare fungal species that has not been described in human invasive infections. In this study, we investigated two T. dohaense isolates from patients with invasive infections in two hospitals in China, as part of the China
Dorival Martins et al.
Scientific reports, 9(1), 9185-9185 (2019-06-27)
Fungi respond to antifungal drugs by increasing their antioxidant stress response. How this impacts antifungal efficacy remains controversial and not well understood. Here we examine the role of catalase activity in the resistance of Saccharomyces cerevisiae to the common antifungals
Shuwen Deng et al.
Emerging microbes & infections, 6(12), e109-e109 (2017-12-07)
This study investigated the triazole phenotype and genotypic of clinical Aspergillus fumigatus isolates from China. We determined the triazole susceptibility profiles of 159 A. fumigatus isolates collected between 2011 and 2015 from four different areas in China tested against 10
Soraya Eugenia Morales-López et al.
Mycopathologia, 181(11-12), 871-878 (2016-09-30)
The presence of the cryptic species belonging to the Candida glabrata complex has not been studied in Argentina. We analyzed a collection of 117 clinical isolates of C. glabrata complex belonging to a National Culture Collection of Instituto Nacional de
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