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Merck
모든 사진(2)

주요 문서

32438

Supelco

Parbendazole

VETRANAL®, analytical standard

동의어(들):

Methyl (5-butyl-1H-benzoimidazol-2-yl)carbamate, Methyl 5(6)-butyl-2-benzimidazolecarbamate

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About This Item

실험식(Hill 표기법):
C13H17N3O2
CAS Number:
Molecular Weight:
247.29
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

analytical standard

Quality Level

제품 라인

VETRANAL®

유통기한

limited shelf life, expiry date on the label

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

forensics and toxicology
pharmaceutical (small molecule)

형식

neat

저장 온도

2-8°C

SMILES string

CCCCc1ccc2nc(NC(=O)OC)[nH]c2c1

InChI

1S/C13H17N3O2/c1-3-4-5-9-6-7-10-11(8-9)15-12(14-10)16-13(17)18-2/h6-8H,3-5H2,1-2H3,(H2,14,15,16,17)

InChI key

YRWLZFXJFBZBEY-UHFFFAOYSA-N

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일반 설명

Parbendazole is a carbamate ester-amine. It finds applications in control or treatment of nematode infestations.

애플리케이션

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

법적 정보

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

픽토그램

Health hazardExclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

P Tejada et al.
Veterinary parasitology, 24(3-4), 269-274 (1987-05-01)
Determinations were made of the inhibitory activities of four benzimidazole anthelmintics (Albendazole, Parbendazole, Mebendazole and Thiabendazole) on purified extracts of cytoplasmic and mitochondrial malate dehydrogenase obtained from Ascaris suum, Fasciola hepatica and Moniezia expansa. The highest percentage inhibitions were exhibited
Inhibition of secretion of proteins and triacylglycerol from isolated rat hepatocytes mediated by benzimidazole carbamate antimicrotubule agents.
C R Birkett et al.
Biochemical pharmacology, 30(12), 1629-1633 (1981-06-15)
M Korenaga et al.
Experimental parasitology, 55(3), 358-363 (1983-06-01)
Immunogenicity of adult Strongyloides ratti was studied in rats. Immunization of rats by intraduodenal implantation of adult worms could completely inhibit the egg production and hasten the expulsion of challenged worms which were developed from subcutaneously inoculated L3 or were
J C Havercroft et al.
Journal of cell science, 49, 195-204 (1981-06-01)
We have shown that the benzimidazole carbamate, parbendazole, is a potent inhibitor of microtubule assembly in vitro and in vivo. Radiolabelled parbendazole was shown to bind to purified tubulin. Immunofluorescence studies using antitubulin antibody showed that parbendazole effectively depolymerizes cytoplasmic
Potentiation by parbendazole of the anthelmintic activity of oxfendazole against natural infections of benzimidazole resistant nematodes.
D R Hennessy et al.
Australian veterinary journal, 64(1), 28-29 (1987-01-01)

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