추천 제품
Grade
analytical standard
Quality Level
제품 라인
VETRANAL®
유통기한
limited shelf life, expiry date on the label
기술
HPLC: suitable
gas chromatography (GC): suitable
응용 분야
forensics and toxicology
pharmaceutical (small molecule)
형식
neat
SMILES string
Oc1c(I)cc(cc1[N+]([O-])=O)C#N
InChI
1S/C7H3IN2O3/c8-5-1-4(3-9)2-6(7(5)11)10(12)13/h1-2,11H
InChI key
SGKGVABHDAQAJO-UHFFFAOYSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Nitroxinil is an anthelmintic agent, which is also an antiparasite. It is highly effective against Fasciola species and its mode of action involves uncoupling the oxidative phosphorylation in liver flukes and also reduces spermatogenesis in surviving flukes, resulting in fewer fertile eggs.
애플리케이션
Nitroxinil may be used as a reference standard in the determination of nitroxinil in veterinary active pharmaceutical ingredient manufacturing and bovine kidney using reversed-phase high-performance liquid chromatography (RP-HPLC) and liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
법적 정보
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
가장 최신 버전 중 하나를 선택하세요:
이미 열람한 고객
J A Tarbin et al.
Journal of chromatography, 613(2), 347-353 (1993-04-02)
A high-performance liquid chromatographic method for the determination of the anthelmintic nitroxynil has been developed. The drug was extracted from cattle muscle tissue with 1% triethylamine in acetonitrile. The extract was evaporated to dryness and taken up in 0.1 M
L Moreno et al.
Research in veterinary science, 88(2), 315-320 (2009-11-07)
The effect of age/body weight in the plasma disposition kinetics of ivermectin (IVM) and nitroxynil (NTX) after their co-administration as a combined formulation to sheep was studied. Sixteen (16) male sheep were allocated into two experimental groups (n=8 each): (a)
Efficacy of nitroxynil against ivermectin, benzimidazole and salicylanilide resistant H contortus.
P C Jeannin et al.
The Veterinary record, 126(25), 624-625 (1990-06-23)
W J Blanchflower et al.
The Analyst, 114(9), 1013-1015 (1989-09-01)
A method is described for the determination of nitroxynil residues in muscle, liver and kidney. The samples were extracted into diethyl ether and cleaned-up using a simple liquid-liquid extraction step. Any nitroxynil present was separated from interfering compounds by high-performance
C Boulard et al.
Veterinary research, 26(4), 249-255 (1995-01-01)
The responses of cattle infected with Fasciola hepatica to treatment with nitroxynil or closantel were monitored by faecal egg counts and by ELISA assay of anti-fluke antibodies. A first trial with experimentally infected heifers showed an increase in anti-fluke antibody
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