383376

Potassium antimonyl tartrate trihydrate

ACS reagent, ≥99%

• 동의어(들): Antimony potassium tartrate trihydrate, Tartar emetic
• 실험식(Hill 표기법): C₈H₄K₂O₁₂Sb₂ · 3H₂O
• CAS Number: 28300-74-5
• Molecular Weight: 667.87
• EC Number: 234-293-3
• MDL number: MFCD00167056
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24863959
• NACRES: NA.21
• 분석: ≥99%; 99.0-103.0%
• Grade: ACS reagent
• 양식: powder
• solubility: water: soluble

속성

• Grade: ACS reagent
• Quality Level: 200
• 분석: ≥99%; 99.0-103.0%
• 양식: powder
• 불순물: ≤0.020 meq/g Titr. acid or base
• 손실: ≤2.7% loss on drying
• mp: ≥300 °C (lit.)
• solubility: water: soluble
• 양이온 미량물: As: ≤0.015%
• SMILES string: O.O.O.[K+].[K+].O=C1O[Sb-]23OC1C4O[Sb-]5(OC(C(O2)C(=O)O3)C(=O)O5)OC4=O
• InChI: 1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4
• InChI key: WBTCZEPSIIFINA-UHFFFAOYSA-J

설명

일반 설명

Potassium antimonyl tartrate trihydrate is a metalloid salt in which the antimony is in trivalent state (SbIII). Potassium antimonyl tartrate (PAT) is an antiparasitic agent predominantly used for treating infections caused by the parasite Leishmania. Its antiangiogenic and antitumor properties has been investigated in nonsmall-cell lung cancer (NSCLC) cells. Studies in Chinese hamster ovary cells show that it may prevent the repair of DNA double strand breaks (DSBs) caused by γ-irradiation.

애플리케이션

Potassium antimonyl tartrate trihydrate has been used in the dose-inhibition experiments to evaluate the dose-inhibition curves of antimony-based antileishmanial compounds against Leishmania promastigotes in medium 199.

Potassium antimonyl tartrate trihydrate may be used to prepare antimony (Sb(III)) stock solution in deionized water (100mg/L). It may also be employed in the spectrophotometric determination of total phosphorus in dry sediments.

안전성 정보

• 픽토그램: GHS06,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H301,H315,H317,H332,H411
• 예방조치 성명서: P261 - P273 - P280 - P301 + P310 - P302 + P352 - P304 + P340 + P312
• Hazard Classifications: Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Skin Irrit. 2 - Skin Sens. 1
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves