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Merck
모든 사진(1)

주요 문서

46609

Supelco

Penicillin G potassium salt

VETRANAL®, analytical standard

동의어(들):

Benzylpenicillin potassium salt

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About This Item

실험식(Hill 표기법):
C16H17KN2O4S
CAS Number:
Molecular Weight:
372.48
Beilstein:
3832841
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
E 번호:
E705
NACRES:
NA.24

Grade

analytical standard

Quality Level

Agency

EPA 1694

제품 라인

VETRANAL®

유통기한

limited shelf life, expiry date on the label

기술

HPLC: suitable
gas chromatography (GC): suitable

항생제 활성 스펙트럼

Gram-positive bacteria

응용 분야

cleaning products
clinical
cosmetics
environmental
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)

형식

neat

동작 모드

cell wall synthesis | interferes

저장 온도

2-8°C

SMILES string

[K+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O

InChI

1S/C16H18N2O4S.K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

InChI key

IYNDLOXRXUOGIU-LQDWTQKMSA-M

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일반 설명

Chemical structure: ß-lactam

애플리케이션

Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

생화학적/생리학적 작용

Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking.

Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.

주의사항

Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The sodium salt is soluble in H2O at 100 mg/mL.

법적 정보

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Vasim Ahmed et al.
Journal of biotechnology, 163(4), 419-424 (2013-01-12)
In the present study, a novel strategy was adopted to synthesize, β lactamase resistant penicillin G molecules by using the unique properties of silver nanoparticles. Ascorbic acid-stabilized spherical monodispersed silver nanoparticles were prepared by a simple chemical reaction. The formation
Tina Lund Leunbach et al.
Ugeskrift for laeger, 175(11), 742-743 (2013-03-14)
A pregnant Caucasian woman with newly diagnosed syphilis in the secondary stage was hospitalized for observation while being treated with penicillin. After one dose of penicillin the foetus was delivered by a caesarean section at gestational age 28 weeks +
Muneki Hotomi et al.
PloS one, 8(3), e58124-e58124 (2013-03-14)
The protection against pneumococcal infections provided by currently available pneumococcal polysaccharide conjugate vaccines are restricted to the limited number of the serotypes included in the vaccine. In the present study, we evaluated the distribution of the pneumococcal capsular type and
Jin-Long Yang et al.
Biofouling, 29(3), 247-259 (2013-03-05)
The effects of bacterial biofilms (BFs) on larval settlement and metamorphosis of the mussel, Mytilus coruscus, were investigated in the laboratory. Of nine different isolates, Shewanella sp.1 BF induced the highest percentage of larval settlement and metamorphosis, whereas seven other
Warunee Punpanich et al.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 95(12), 1606-1612 (2013-02-09)
A case of 6-week-old male infant with meningitis and concurrent bacteremia caused by Streptococcus gallolyticus subspecies pasteurianus (Streptococcus bovis biotype 11.2) is presented. The isolates were susceptible to all beta-lactam antibiotics. Nevertheless, delayed defervescence and lack of satisfactory clinical improvement

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