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Merck
모든 사진(3)

주요 문서

51964

Supelco

Valerenic acid

analytical standard

동의어(들):

(2E)-3-[(4S,7R,7aR)-2,4,5,6,7,7a-Hexadydro-3,7-dimethyl- 1H-inden-4-yl]-2-methyl-2-propenoic acid

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About This Item

실험식(Hill 표기법):
C15H22O2
CAS Number:
Molecular Weight:
234.33
Beilstein:
3138020
MDL number:
UNSPSC 코드:
85151701
PubChem Substance ID:
NACRES:
NA.24

Grade

analytical standard

Quality Level

분석

≥98.0% (HPLC)

유통기한

limited shelf life, expiry date on the label

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

cleaning products
cosmetics
food and beverages
personal care

형식

neat

저장 온도

−20°C

SMILES string

[H][C@]12CCC(C)=C1[C@@H](CC[C@H]2C)\C=C(/C)C(O)=O

InChI

1S/C15H22O2/c1-9-4-6-12(8-11(3)15(16)17)14-10(2)5-7-13(9)14/h8-9,12-13H,4-7H2,1-3H3,(H,16,17)/b11-8+/t9-,12+,13-/m1/s1

InChI key

FEBNTWHYQKGEIQ-SUKRRCERSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Valerenic acid is a bioactive sesquiterpene and a natural product, isolated from Valeriana officinalis type of plant. It can find applications in the treatment of several dis-functions of the central nervous system, since it is potent modulator of the GABAA receptor.

애플리케이션

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

기타 정보

Constituent of Valeriana officinalis

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

P J Houghton
The Journal of pharmacy and pharmacology, 51(5), 505-512 (1999-07-20)
The underground organs of members of the genus Valeriana (Valerianaceae), as well as related genera such as Nardostachys, are used in the traditional medicine of many cultures as mild sedatives and tranquillizers and to aid the induction of sleep. V.
Juergen Ramharter et al.
Organic letters, 13(19), 5310-5313 (2011-09-08)
A mild and selective one-pot procedure to provide 2,4-dienols from simple cycloalkenones in high yields is described. This transformation is based on the in situ formation of acid-labile allylic alcohols, which on treatment with trifluoroacetic acid undergo a formal [1,3]-hydroxy
Highly potent modulation of GABA(A) receptors by valerenic acid derivatives.
Sascha Kopp et al.
ChemMedChem, 5(5), 678-681 (2010-03-18)
Takashi Kitayama et al.
Bioscience, biotechnology, and biochemistry, 74(9), 1963-1964 (2010-09-14)
A concise synthesis of valerena-4,7(11)-diene with potent sedative activity was achieved in three steps involving, reduction of carboxylic acid, bromination of the resulting alcohol, and reduction of the bromide from valerenic acid in a 63% total yield. This synthetic method
Nicholas K Chow et al.
Planta medica, 77(8), 795-803 (2010-12-15)
Valeriana officinalis L. is a popular herbal treatment for mild sleep disorders. Clinical and non-clinical studies found contradictory results for valerian extracts and single constituents regarding the influence on sleep parameters. It was the aim of this study to investigate

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