52517
1,1,1,3,3,3-Hexafluoro-2-propanol
for GC derivatization, LiChropur™, ≥99.8%
동의어(들):
HFP, Hexafluoroisopropanol
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
Linear Formula:
(CF3)2CHOH
CAS Number:
Molecular Weight:
168.04
Beilstein:
1841007
EC Number:
MDL number:
UNSPSC 코드:
12352104
PubChem Substance ID:
NACRES:
NA.05
추천 제품
Grade
for GC derivatization
Quality Level
분석
≥99.8% (GC)
≥99.8%
품질
LiChropur™
반응 적합성
reagent type: derivatization reagent
reaction type: Acylations
reagent type: derivatization reagent
reaction type: Esterifications
기술
gas chromatography (GC): suitable
refractive index
n20/D 1.275 (lit.)
bp
59 °C (lit.)
mp
−4 °C (lit.)
density
1.596 g/mL at 25 °C (lit.)
SMILES string
OC(C(F)(F)F)C(F)(F)F
InChI
1S/C3H2F6O/c4-2(5,6)1(10)3(7,8)9/h1,10H
InChI key
BYEAHWXPCBROCE-UHFFFAOYSA-N
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일반 설명
Hexafluoroisopropanol (HFP) is generally used to denature the native state of proteins, and it also stabilizes the a-helical conformation in unfolded peptides and proteins like ß-lactoglobulin and melittin.
애플리케이션
Suitable for the derivatization of glutamic acid, homovanillic, iso-homovanillic and dihydroxyphenyl acetic acids and Υ-aminobutyric acid.
기타 정보
Reagent for hexafluoroisopropyl ester, N-pentafluoropropionyl, and trifluoroacetyl..
Size-exclusion chromatography in 1,1,1,3,3,3-hexafluoro-2-propanol
법적 정보
LiChropur is a trademark of Merck KGaA, Darmstadt, Germany
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Eye Dam. 1 - Repr. 2 - Skin Corr. 1A - STOT RE 2
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 2
Flash Point (°F)
No data available
Flash Point (°C)
No data available
개인 보호 장비
Faceshields, Gloves, Goggles
이미 열람한 고객
Thomas H Mourey et al.
Journal of chromatography. A, 964(1-2), 169-178 (2002-08-30)
1,1,1,3,3,3-Hexafluoroisopropanol is re-examined as an eluent for size-exclusion chromatography (SEC) of polyesters, nylons, and other polar polymers. It is shown that anomalous SEC behavior reported in previous literature can be eliminated by adding 0.01 M tetraethylammonium nitrate to the eluent.
Yao Chen et al.
Journal of enzyme inhibition and medicinal chemistry, 33(1), 290-302 (2017-12-28)
Small molecule cholinesterases inhibitor (ChEI) provides an effective therapeutic strategy to treat Alzheimer's disease (AD). Currently, the discovery of new ChEI with multi-target effect is still of great importance. Herein, we report the synthesis, structure-activity relationship study and biological evaluation
Cooperative a-helix formation of ?-lactoglobulin and melittin induced by hexafluoroisopropanol
Hirota, Nami, Yuji Goto, and Kazuko Mizuno.
Protein Science, 6 (2), 416-421 (1997)
Sriya Das et al.
ACS applied materials & interfaces, 3(6), 1844-1851 (2011-05-05)
We demonstrate a novel in situ polymerization technique to develop localized polymer coatings on the surface of dispersed pristine graphene sheets. Graphene sheets show great promise as strong, conductive fillers in polymer nanocomposites; however, difficulties in dispersion quality and interfacial
Jie Zhu et al.
Journal of enzyme inhibition and medicinal chemistry, 33(1), 496-506 (2018-02-07)
The cholinergic hypothesis has long been a "polar star" in drug discovery for Alzheimer's disease (AD), resulting in many small molecules and biological drug candidates. Most of the drugs marketed for AD are cholinergic. Herein, we report our efforts in
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