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Merck
모든 사진(2)

주요 문서

95162

Supelco

2,3,5,6-Tetramethylpyrazine

analytical standard

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About This Item

실험식(Hill 표기법):
C8H12N2
CAS Number:
Molecular Weight:
136.19
Beilstein:
113100
EC Number:
MDL number:
UNSPSC 코드:
85151701
PubChem Substance ID:
NACRES:
NA.24

Grade

analytical standard

Quality Level

분석

≥98.0% (GC)

유통기한

limited shelf life, expiry date on the label

기술

HPLC: suitable
gas chromatography (GC): suitable

bp

190 °C (lit.)

mp

77-80 °C (lit.)
85-87 °C

응용 분야

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

형식

neat

SMILES string

Cc1nc(C)c(C)nc1C

InChI

1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3

InChI key

FINHMKGKINIASC-UHFFFAOYSA-N

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일반 설명

2,3,5,6-Tetramethylpyrazine is a flavor compound belonging to the class of pyrazines. It is found to be a main active ingredient of the traditional Chinese medicine, Chuanxiong and Ma-Huang herbs, used to treat asthma.

애플리케이션

2,3,5,6-Tetramethylpyrazine may be used as an analytical reference standard for the quantification of the analyte in Ephedrae herba and Ephedra sinica Stapf using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Applications of Microbial Engineering (2013)
Analysis of tetramethylpyrazine in Ephedrae herba by gas chromatography?mass spectrometry and high-performance liquid chromatography
Lv K, et al.
Journal of Chromatography A, 878(1), 147-152 (2000)
Separation and determination of ephedrine alkaloids and tetramethylpyrazine in ephedra sinica Stapf by gas chromatography-mass spectrometry
Journal of Chromatographic Science, 39(9), 370-374 (2001)
Shouliang Wang et al.
Drug design, development and therapy, 13, 1187-1196 (2019-05-23)
Background: Bupivacaine (BUP) acts as a local anesthetic, which is extensively used for clinical patients but could generate neurotoxicity in neurons. Tetramethylpyrazine (TET) exhibits strong neuron protective effects against neurotoxicity. Hence, we investigate the effect of TET on BUP-induced neurotoxicity
Yu-Fang Leng et al.
The American journal of Chinese medicine, 40(6), 1229-1239 (2012-12-12)
The Bennett and Xie (1988) model of chronic constriction injury (CCI) investigated the effects of tetramethylpyrazine (TMP) on neuropathic pain-associated behaviors and neuronal apoptosis in the spinal dorsal horn. Fifty-four male rats were randomly divided into sham (group S), CCI

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