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Merck
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주요 문서

D0720800

Dexchlorpheniramine maleate

European Pharmacopoeia (EP) Reference Standard

동의어(들):

S-(+)-Chlorpheniramine maleate salt, (S)-γ-(4-Chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine maleate salt

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About This Item

실험식(Hill 표기법):
C16H19ClN2 · C4H4O4
CAS Number:
Molecular Weight:
390.86
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

pharmaceutical primary standard

API family

dexchlorpheniramine

제조업체/상표

EDQM

응용 분야

pharmaceutical (small molecule)

형식

neat

SMILES string

[H]\C(=C(/[H])C(O)=O)C(O)=O.CN(C)CC[C@@H](c1ccc(Cl)cc1)c2ccccn2

InChI

1S/C16H19ClN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-;/m0./s1

InChI key

DBAKFASWICGISY-DASCVMRKSA-N

유전자 정보

human ... HRH1(3269)

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일반 설명

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션

Dexchlorpheniramine maleate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

포장

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

기타 정보

Sales restrictions may apply.

픽토그램

Skull and crossbones

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

P van Ruitenbeek et al.
Journal of psychopharmacology (Oxford, England), 22(6), 663-672 (2008-01-23)
Results from recent animal studies suggest an important role for histamine in memory functioning. Histaminergic drugs might prove beneficial for people suffering from memory impairment. To determine if histamine is involved in memory functioning this study evaluates the effects of
Ronilson Agnaldo Moreno et al.
Biomedical chromatography : BMC, 24(7), 774-781 (2009-11-20)
In the present study a fast, sensitive and robust validated method to quantify chlorpheniramine in human plasma using brompheniramine as internal standard (IS) is described. The analyte and the IS were extracted from plasma by LLE (diethyl ether-dichloromethane, 80:20, v/v)
P van Ruitenbeek et al.
British journal of pharmacology, 157(1), 76-85 (2009-02-18)
Centrally active antihistamines impair cognitive performance, particularly sensorimotor performance. The aim of the present study was to further elucidate the scarcely studied subprocesses involved in sensorimotor performance, which may be affected by H1 receptor blockade. Better knowledge about the cognitive
Shirlei Cristina Moreira et al.
Revista da Sociedade Brasileira de Medicina Tropical, 40(5), 591-593 (2007-11-10)
An occurrence of pruritic papular dermatitis among the whole crew of a Filipino commercial ship in Salvador, State of Bahia, was associated with contact with Hylesia moths. This unusual type of dermatitis is caused by the bristles (flechettes) on the
P Van Ruitenbeek et al.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 20(4), 226-235 (2010-01-20)
Animal literature suggests an important role for histamine in memory. In humans, this hypothesis has been scarcely tested and results from studies that have addressed this are conflicting. Second, impaired memory performance may be secondary to sedation. This study aimed

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