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Merck
모든 사진(1)

주요 문서

D2963000

Doxapram hydrochloride

European Pharmacopoeia (EP) Reference Standard

동의어(들):

Doxapram hydrochloride monohydrate, 1-Ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-2-pyrrolidinone monohydrochloride monohydrate

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About This Item

실험식(Hill 표기법):
C24H30N2O2 · HCl · H2O
CAS Number:
Molecular Weight:
432.98
UNSPSC 코드:
41116107
NACRES:
NA.24

Grade

pharmaceutical primary standard

API family

doxapram

제조업체/상표

EDQM

응용 분야

pharmaceutical (small molecule)

형식

neat

InChI

1S/C24H30N2O2.ClH.H2O/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21;;/h3-12,22H,2,13-19H2,1H3;1H;1H2

InChI key

ZOMBFZRWMLIDPX-UHFFFAOYSA-N

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일반 설명

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션

Doxapram hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

포장

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

기타 정보

Sales restrictions may apply.

픽토그램

Skull and crossbones

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Daihua Yu et al.
Canadian journal of anaesthesia = Journal canadien d'anesthesie, 57(9), 843-848 (2010-06-08)
The study was designed to determine the incidence of postoperative agitation following general anesthesia in 2,000 adult patients and to examine the associated risk factors. The study enrolled 2,000 adults who were scheduled for surgery under general anesthesia in a
Dennis J Murphy et al.
Journal of pharmacological and toxicological methods, 62(1), 47-53 (2010-05-04)
Assessing the effects of new chemical entities on respiratory function in animal models is an essential component of preclinical drug safety evaluation. Methods currently available for measuring ventilatory parameters in conscious dogs generally utilize a plethysmograph chamber or a face
Steeve Giguère et al.
American journal of veterinary research, 68(12), 1407-1416 (2007-12-07)
To determine and compare the effects of caffeine and doxapram on cardiorespiratory variables in foals during isoflurane-induced respiratory acidosis. 6 clinically normal foals (1 to 3 days old). At intervals of > or = 24 hours, foals received each of
J J P Goldring et al.
British journal of hospital medicine (London, England : 2005), 69(8), 444-449 (2008-09-12)
Acute-on-chronic respiratory failure is becoming an increasingly common medical emergency, mostly as a result of exacerbations of chronic obstructive pulmonary disease. It is associated with high mortality rates and so practising the best evidence-based management is vital.
A Greenough et al.
Archives of disease in childhood. Fetal and neonatal edition, 93(3), F242-F245 (2007-11-17)
Randomised trials have demonstrated that ventilation techniques which support every spontaneous breath are the most efficacious weaning modes. Nasal continuous positive airway pressure after extubation reduces the likelihood of incidents leading to the need for reintubation in very low birthweight

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