E6133

Ethanolamine hydrochloride

≥99.0%

• 동의어(들): mea hydrochloride, monoethanolamine hydrochloride, 2-Aminoethanol hydrochloride
• Linear Formula: H₂NCH₂CH₂OH · HCl
• CAS Number: 2002-24-6
• Molecular Weight: 97.54
• Beilstein: 3542892
• EC Number: 217-900-6
• MDL number: MFCD00012892
• UNSPSC 코드: 12161700
• PubChem Substance ID: 57654165
• NACRES: NA.25

속성

• Quality Level: 300
• 분석: ≥99.0%
• 형태: powder or crystals
• 저장 조건: dry at room temperature
• 기술: HPLC: suitable
• 색상: white
• pH: 9—10
• pKa(25 °C): 9.5
• mp: 82-84 °C (lit.)
• solubility: water: 0.33 g/mL, clear, colorless to very faintly yellow
• density: 1.07 g/cm³ at 20—25 °C; 1.12 g/cm³ at 20—25 °C
• 적합성: suitable for chromatography
• 응용 분야: general analytical; life science and biopharma; pharmaceutical
• SMILES string: NCCO.[H]Cl
• InChI: 1S/C2H7NO.ClH/c3-1-2-4;/h4H,1-3H2;1H
• InChI key: PMUNIMVZCACZBB-UHFFFAOYSA-N

설명

일반 설명

Ethanolamine hydrochloride, a versatile compound in biochemistry and molecular biology, plays a pivotal role in diverse research areas. Primarily, it functions as a buffering agent, ensuring a stable pH environment crucial for enzymatic reactions, protein solubilization, and other biological processes. Its significance extends to membrane protein studies, aiding in the extraction of these proteins from cell membranes. It also finds utility in cell culture and as a reagent for biological sample preparation, simplifying nucleic acid and protein isolation, as well as facilitating the detection of proteins by western blotting and immunohistochemistry. This compound′s wide-ranging applications make it indispensable in biochemical research, contributing to various experimental procedures and advancing our understanding in fields such as molecular biology, immunology, and cellular biology.

애플리케이션

Ethanolamine hydrochloride has been used:

• in overnight incubation of the tips to attach primary amine groups at the tip surface
• in the preparation of DMEM (dulbecco′s modified eagle′s medium)/F-12 media to culture human epidermal growth factor receptor 2 (HER2) cells derived from MMTV-HER2 transgenic mouse mammary tumors
• to administer the cultures to study its effect on the endogenous phosphatidyl ethanolamine pool and autophagy process
• in a study as a reagent to study molecular interactions and adhesion forces in biological systems using Atomic Force Microscopy
• to prepare the reagent for surface-enhanced laser desorption ionization analysis, aimed at studying the role of Interleukins

생화학적/생리학적 작용

Ethanolamine hydrochloride is utilized as a carbon and nitrogen source by bacteria that differs phylogenetically. It exists as phosphotidylethanolamine in the bacterial and mammalian cell membrane. Ethanolamine-ammonia lyase is responsible for the degradation of ethanolamine into acetaldehyde and ammonia. Ethanolamine is known to positively support lipid accumulation in photosynthetic organism model.

특징 및 장점

• Suitable for Immunology, Cellular Biology and Biochemical Research
• Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications
• Effective Buffering Agent with a pKa of 9.5 (25 °C)

기타 정보

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안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302 + H312 + H332,H315,H319,H335,H412
• 예방조치 성명서: P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves