H5501

Methyl 4-hydroxybenzoate

ReagentPlus^®, ≥99.0%, crystalline

• 동의어(들): p-Hydroxybenzoic acid methyl ester, Methyl paraben, NIPAGIN
• Linear Formula: HOC₆H₄CO₂CH₃
• CAS Number: 99-76-3
• Molecular Weight: 152.15
• Beilstein: 509801
• EC Number: 202-785-7
• MDL number: MFCD00002352
• UNSPSC 코드: 51452201
• PubChem Substance ID: 329815219
• NACRES: NA.25

속성

• Quality Level: 200
• 제품 라인: ReagentPlus^®
• 분석: ≥99.0%
• 형태: crystalline
• mp: 125-128 °C (lit.)
• SMILES string: COC(=O)c1ccc(O)cc1
• InChI: 1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3
• InChI key: LXCFILQKKLGQFO-UHFFFAOYSA-N

설명

애플리케이션

Methyl 4-hydroxybenzoate has been used:

• in sex-linked recessive lethal (SLRL) test in Drosophila melanogaster
• as a constituent in cream formulation
• as an antifungal agent in Drosophila melanogaster culture

생화학적/생리학적 작용

Methyl 4-hydroxybenzoate, also called methyl paraben or nipagin, comprises the ester of p-hydroxybenzoic acid. It is present naturally in cloudberry, white wine and bourbon vanilla. Methyl 4-hydroxybenzoate has antimicrobial and antifungal functionality and is commercially used as a preservative in the food, cosmetic and pharmaceutical industry. Methyl 4-hydroxybenzoate has cytotoxic effects on keratinocytes in the presence of sunlight. Methyl 4-hydroxybenzoate upon solar irradiation mediates DNA damage and modulates esterase metabolism resulting in skin damage and favors cancer progression. Methyl 4-hydroxybenzoate has estrogenic functionality and upregulates estrogen-related genes.

법적 정보

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

안전성 정보

• 픽토그램: GHS09
• 유해 및 위험 성명서: H411
• 예방조치 성명서: P273 - P391 - P501
• Hazard Classifications: Aquatic Chronic 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): 334.4 °F
• Flash Point (°C): 168 °C
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves