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Merck
모든 사진(1)

주요 문서

I0775010

Isosorbide mononitrate

European Pharmacopoeia (EP) Reference Standard

동의어(들):

1,4:3,6-Dianhydro-D-glucitol 5-nitrate

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About This Item

실험식(Hill 표기법):
C6H9NO6
CAS Number:
Molecular Weight:
191.14
EC Number:
UNSPSC 코드:
41116107
NACRES:
NA.24

Grade

pharmaceutical primary standard

API family

isosorbide

제조업체/상표

EDQM

응용 분야

pharmaceutical (small molecule)

형식

neat

저장 온도

2-8°C

InChI

1S/C6H9NO6/c8-3-1-11-6-4(13-7(9)10)2-12-5(3)6/h3-6,8H,1-2H2/t3-,4+,5+,6+/m0/s1

InChI key

YWXYYJSYQOXTPL-SLPGGIOYSA-N

일반 설명

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션

Isosorbide mononitrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

포장

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

기타 정보

Sales restrictions may apply.

픽토그램

Flame

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Flam. Sol. 1

Storage Class Code

4.1A - Other explosive hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

죄송합니다. 지금은 이 제품에 대한 COA이(가) 온라인에서 제공되지 않습니다.

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문서 라이브러리 방문

Mark J Bolland et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 35(6), 1040-1047 (2020-05-07)
Organic nitrates have been reported to have significant effects on bone mineral density (BMD) and bone turnover in previous clinical trials. However, results are inconsistent and some trials with strikingly positive results have been retracted because of scientific misconduct. As
Yuan Li et al.
Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc, 46(2), 145-152 (2019-05-06)
Hyperbaric oxygen (HBO2) therapy improves myocardial function and reduces clinical restenosis in coronary arteries. This study aims to evaluate whether the HBO2 therapy can improve vascular endothelial dysfunction in patients undergoing coronary stent implantation. The retrospective study included 115 patients
Priyadarshani Galappatthy et al.
Heart (British Cardiac Society), 104(17), 1424-1431 (2018-02-18)
Ischaemic heart disease is the leading cause of in-hospital mortality in Sri Lanka. Acute Coronary Syndrome Sri Lanka Audit Project (ACSSLAP) is the first national clinical-audit project that evaluated patient characteristics, clinical outcomes and care provided by state-sector hospitals. ACSSLAP
U W Abshagen
The American journal of cardiology, 70(17), 61G-66G (1992-11-27)
Pharmacokinetic studies show that isosorbide mononitrate is rapidly absorbed after oral administration, reaches peak concentrations within an hour, undergoes no significant first-pass metabolism, and is virtually 100% bioavailable. The half-life is approximately 5 hours, the volume of distribution is 0.62
Athanasios Mousiolis et al.
Contraception, 88(1), 41-44 (2013-01-08)
Isosorbide mononitrate (IMN) administration is thought to enhance in the cervical ripening process. We sought to identify the clinical usefulness and safety of IMN administration for shortening the time to termination of the second trimester pregnancy procedures when used in

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