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Merck
모든 사진(1)

문서

PHR1277

Supelco

Nitrilotriacetic acid

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

Nitrilotriacetic acid, N,N-Bis(carboxymethyl)glycine, NTA, Tris(carboxymethyl)amine

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About This Item

Linear Formula:
N(CH2COOH)3
CAS Number:
Molecular Weight:
191.14
Beilstein:
1710776
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to USP 1463950

API family

edta

CofA

current certificate can be downloaded

기술

HPLC: suitable
gas chromatography (GC): suitable

mp

245 °C (dec.) (lit.)

응용 분야

pharmaceutical (small molecule)

형식

neat

저장 온도

2-8°C

SMILES string

OC(=O)CN(CC(O)=O)CC(O)=O

InChI

1S/C6H9NO6/c8-4(9)1-7(2-5(10)11)3-6(12)13/h1-3H2,(H,8,9)(H,10,11)(H,12,13)

InChI key

MGFYIUFZLHCRTH-UHFFFAOYSA-N

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일반 설명

Nitrilotriacetic acid (NTA) is a polyaminopolycarboxylic acid, widely used as a synthetic chelating agent. It forms stable and water-soluble chelates with different metals. It is used as a detergent builder to soften water and for masking metal ions in various industrial processes.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

애플리케이션

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
An excellent chelating agent.

분석 메모

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

기타 정보

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

각주

To see an example of a Certificate of Analysis for this material enter LRAC3702 in the slot below. This is an example certificate only and may not be the lot that you receive.

추천 제품

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

픽토그램

Health hazardExclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

212.0 °F - closed cup

Flash Point (°C)

100 °C - closed cup


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Determination of nitrilotriacetic acid and ethylenediaminetetraacetic acid in environmental samples as their methyl ester derivatives by gas chromatography-mass spectrometry
Nishikawa Y and Okumura T
Journal of Chromatography A, 690(1), 109-118 (1995)
Quantitative gas chromatographic determination of nitrilotriacetic acid in the presence of other carboxylic acids
Larson RA, et al.
Journal of Chromatography A, 111(1), 43-49 (1975)
The determination of part-per-billion levels of citric and nitrilotriacetic acids in tap water and sewage effluents
Aue WA, et al.
Journal of Chromatography A, 72(2), 259-267 (1972)
Determination of the solubility products of nitrilotriacetic acid, ethylenediaminetetraacetic acid and diethylenetriaminepentaacetic acid.
Karhu J, et al.
Analytica Chimica Acta, 380(1), 105-111 (1999)
R L Anderson et al.
Critical reviews in toxicology, 15(1), 1-102 (1985-01-01)
This article provides a review of available information on the chemistry, environmental toxicology, and mammalian toxicology of nitrilotriacetic acid (NTA). The ability of NTA to chelate metal ions such as Mg++ and Ca++ into water soluble complexes makes NTA useful

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