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Merck
모든 사진(1)

주요 문서

PHR1686

Supelco

Tazobactam

Pharmaceutical Secondary Standard; Certified Reference Material

동의어(들):

Tazobactam, (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo-[3.2.0]heptanes-2-carboxylicacid-4,4-dioxide, [2S-(2α,3β,5α)]-3-Methyl-7-oxo-3-(1H,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptan-2-carbonsäure-4,4-dioxid

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About This Item

실험식(Hill 표기법):
C10H12N4O5S
CAS Number:
Molecular Weight:
300.29
UNSPSC 코드:
41116107
NACRES:
NA.24

Grade

certified reference material
pharmaceutical secondary standard

Quality Level

Agency

traceable to USP 1643383

API family

tazobactam

CofA

current certificate can be downloaded

포장

pkg of 1 g

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

pharmaceutical (small molecule)

형식

neat

저장 온도

2-8°C

InChI

1S/C10H12N4O5S/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19/h2-3,7-8H,4-5H2,1H3,(H,16,17)/t7-,8+,10+/m1/s1

InChI key

LPQZKKCYTLCDGQ-WEDXCCLWSA-N

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일반 설명

Tazobactam is a penicillanic acid sulfone used in combination with β-lactamase antibiotic as antibacterial to reduce the development of drug-resistant bacteria.

애플리케이션

Tazobactam may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using reversed-phase high-performance liquid chromatography technique.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

분석 메모

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

기타 정보

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

각주

To see an example of a Certificate of Analysis for this material enter LRAA6302 in the slot below. This is an example certificate only and may not be the lot that you receive.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

이미 열람한 고객

Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 7(9), 127-131 (2019)
Simultaneous determination of piperacillin and tazobactam in pharmaceutical formulations by RP-HPLC method
Veni KRP, et al.
Journal of Pharmacy Research, 7(1), 127-131 (2013)
Emily Marsh et al.
Clinica chimica acta; international journal of clinical chemistry, 486, 265-268 (2018-08-18)
Therapeutic drug monitoring is used for aminoglycosides and vancomycin, and has been proposed for β-lactam antibiotics. Clinical blood samples in the ICU are often obtained via an existing vascular catheter rather than fresh needle phlebotomy. If antibiotics had previously been

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