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Merck
모든 사진(1)

주요 문서

375810

Sigma-Aldrich

Periodic acid

ACS reagent, 99%

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About This Item

실험식(Hill 표기법):
H5IO6
CAS Number:
Molecular Weight:
227.94
EC Number:
MDL number:
UNSPSC 코드:
12352106
PubChem Substance ID:
NACRES:
NA.21
Grade:
ACS reagent

Grade

ACS reagent

Quality Level

분석

99%
99.0-101.0% (ACS specification)

양식

powder or crystals

반응 적합성

reaction type: C-H Activation
reagent type: catalyst
reagent type: oxidant

불순물

≤0.01% insolubles
≤0.01% other halogens

무기 잔류물

≤0.01%

mp

122 °C (lit.)

solubility

water: soluble

음이온 미량물

sulfate (SO42-): ≤0.01%

양이온 미량물

Fe: ≤0.003%
heavy metals: ≤0.005%

응용 분야

histology

SMILES string

OI(O)(O)(O)(O)=O

InChI

1S/H5IO6/c2-1(3,4,5,6)7/h(H5,2,3,4,5,6,7)

InChI key

TWLXDPFBEPBAQB-UHFFFAOYSA-N

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일반 설명

Periodic acid is an inorganic acid commonly used as an oxidizing agent. Periodic acid oxidation is one of the steps in the periodate-resorcinol assay, used in the determination of sialic acid. Periodic acid reacts with 1,2 glycol linkage of carbohydrates to form aldehydes which can be stained by Schiff′s reagent. Therefore periodic-acid-Schiff′s reagent (PAS) is used in histochemistry to determine carbohydrates in tissue sections.

애플리케이션

Periodic acid may be used in the following reactions:
  • Oxidation of alcohols to ketones and aldehydes.
  • Oxidation hydroxylamine derivatives.
  • Oxidation of arenes to quinones.
  • Deprotection of the dithio- and oxathio-derivatives.
  • Oxidative degradation of epoxidized natural rubber (ENR).
  • Oxidation of urazoles and bis-urazoles to triazolinediones.
  • Oxidative cleavage of glucosazone.

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Ox. Sol. 1 - Skin Corr. 1B - STOT RE 1 Oral

표적 기관

Thyroid

Storage Class Code

5.1A - Strongly oxidizing hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Deblocking of dithioacetals and oxathioacetals using periodic acid under mild nonaqueous conditions.
Shi XX, et al.
Tetrahedron Letters, 37(25), 4331-4334 (1996)
The Action of Periodic Acid on Glucose Phenylosazone.
Chargaff E and Magasanik B.
Journal of the American Chemical Society, 69(6), 1459-1461 (1947)
The sialic acids. XI. A periodate-resorcinol method for the quantitative estimation of free sialic acids and their glycosides.
G W Jourdian et al.
The Journal of biological chemistry, 246(2), 430-435 (1971-01-25)
A mild and efficient oxidation of alcohols to aldehydes and ketones with periodic acid catalyzed by chromium (III) acetylacetonate.
Xu L and Trudell ML.
Tetrahedron Letters, 44(12), 2553-2555 (2003)
Histological and histochemical uses of periodic acid.
J F A McMANUS
Stain technology, 23(3), 99-108 (1948-07-01)

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