추천 제품
Grade
ACS reagent
Quality Level
분석
99%
99.0-101.0% (ACS specification)
양식
powder or crystals
반응 적합성
reaction type: C-H Activation
reagent type: catalyst
reagent type: oxidant
불순물
≤0.01% insolubles
≤0.01% other halogens
무기 잔류물
≤0.01%
mp
122 °C (lit.)
solubility
water: soluble
음이온 미량물
sulfate (SO42-): ≤0.01%
양이온 미량물
Fe: ≤0.003%
heavy metals: ≤0.005%
응용 분야
histology
SMILES string
OI(O)(O)(O)(O)=O
InChI
1S/H5IO6/c2-1(3,4,5,6)7/h(H5,2,3,4,5,6,7)
InChI key
TWLXDPFBEPBAQB-UHFFFAOYSA-N
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일반 설명
Periodic acid is an inorganic acid commonly used as an oxidizing agent. Periodic acid oxidation is one of the steps in the periodate-resorcinol assay, used in the determination of sialic acid. Periodic acid reacts with 1,2 glycol linkage of carbohydrates to form aldehydes which can be stained by Schiff′s reagent. Therefore periodic-acid-Schiff′s reagent (PAS) is used in histochemistry to determine carbohydrates in tissue sections.
애플리케이션
Periodic acid may be used in the following reactions:
- Oxidation of alcohols to ketones and aldehydes.
- Oxidation hydroxylamine derivatives.
- Oxidation of arenes to quinones.
- Deprotection of the dithio- and oxathio-derivatives.
- Oxidative degradation of epoxidized natural rubber (ENR).
- Oxidation of urazoles and bis-urazoles to triazolinediones.
- Oxidative cleavage of glucosazone.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Ox. Sol. 1 - Skin Corr. 1B - STOT RE 1 Oral
표적 기관
Thyroid
Storage Class Code
5.1A - Strongly oxidizing hazardous materials
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Deblocking of dithioacetals and oxathioacetals using periodic acid under mild nonaqueous conditions.
Tetrahedron Letters, 37(25), 4331-4334 (1996)
The Action of Periodic Acid on Glucose Phenylosazone.
Journal of the American Chemical Society, 69(6), 1459-1461 (1947)
The sialic acids. XI. A periodate-resorcinol method for the quantitative estimation of free sialic acids and their glycosides.
The Journal of biological chemistry, 246(2), 430-435 (1971-01-25)
A mild and efficient oxidation of alcohols to aldehydes and ketones with periodic acid catalyzed by chromium (III) acetylacetonate.
Tetrahedron Letters, 44(12), 2553-2555 (2003)
Histological and histochemical uses of periodic acid.
Stain technology, 23(3), 99-108 (1948-07-01)
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