08450

7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester

BioReagent, suitable for fluorescence, ≥90% (HPLC)

• 동의어(들): 7-(Dimethylamino)coumarin-4-acetic acid-NHS, 7-Amino-4-methyl-3coumarinylacetyl, N-Succinimidyl 7-amino-4-methyl-3-coumarinylacetate, AMCA-NHS, Succinimidyl-7-amino-4-methylcoumarin-3-acetate
• 실험식(Hill 표기법): C₁₆H₁₄N₂O₆
• CAS Number: 113721-87-2
• Molecular Weight: 330.29
• Beilstein: 9007679
• MDL number: MFCD00036170
• UNSPSC 코드: 12352108
• PubChem Substance ID: 329748586
• NACRES: NA.32

속성

• 제품 라인: BioReagent
• Quality Level: 100
• 분석: ≥90% (HPLC)
• solubility: DMF: soluble; DMSO: soluble
• 형광: λ_ex 354 nm; λ_em 440 nm in methanol
• 적합성: suitable for fluorescence
• 저장 온도: −20°C
• SMILES string: CC1=C(CC(=O)ON2C(=O)CCC2=O)C(=O)Oc3cc(N)ccc13; CC1=C(CC(=O)ON2C(=O)CCC2=O)C(=O)Oc3cc(N)ccc13
• InChI: 1S/C16H14N2O6/c1-8-10-3-2-9(17)6-12(10)23-16(22)11(8)7-15(21)24-18-13(19)4-5-14(18)20/h2-3,6H,4-5,7,17H2,1H3
• InChI key: ILKQVTIMOGNSAS-UHFFFAOYSA-N

설명

애플리케이션

AMCA-NHS has been utilized in the development of a donor europium chelate fluorochrome for use in LRET based analyses by first reacting with an amino group and then with DTPA anhydride . Utilized in FRET based studies, acting as the donor dye and can be paired with fluorescein-5-isothiocyanate as the acceptor dye . A blue fluorescent dye reactive towards primary amine groups on proteins, peptides, antibodies, and other biomolecules (at pH 7.0-9.0).

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

기타 정보

Labeling of lysyl residues in proteins

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves