추천 제품
생물학적 소스
bovine spinal cord
Quality Level
분석
≥98.0% (TLC)
양식
solid
불순물
α-hydroxy fatty acids
solubility
chloroform/methanol (99:1): 20 mg/mL, clear, colorless
지질 유형
sphingolipids
배송 상태
wet ice
저장 온도
−20°C
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관련 카테고리
애플리케이션
Ceramide is used to investigate effects on programmed cell death (apoptosis) and insulin signaling.
생화학적/생리학적 작용
Ceramide is a minor component of cell membranes. Activates atypical protein kinase C (e.g., PKCzeta) .
제조 메모
from cerebrosides by a modification of the procedure by H.E. Carter et al., J. Lipid Res. 2, 228 (1961)
기타 정보
Sales restrictions may apply
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
Darren J Powell et al.
Molecular and cellular biology, 23(21), 7794-7808 (2003-10-16)
Ceramide is generated in response to numerous stress-inducing stimuli and has been implicated in the regulation of diverse cellular responses, including cell death, differentiation, and insulin sensitivity. Recent evidence indicates that ceramide may regulate these responses by inhibiting the stimulus-mediated
Huijing Yin et al.
Nature communications, 12(1), 4230-4230 (2021-07-11)
Extracellular matrix protein-1 (ECM1) promotes tumorigenesis in multiple organs but the mechanisms associated to ECM1 isoform subtypes have yet to be clarified. We report in this study that the secretory ECM1a isoform induces tumorigenesis through the GPR motif binding to
M G Yefimova et al.
Human reproduction (Oxford, England), 35(6), 1346-1362 (2020-06-13)
Do human granulosa cells (GCs) ingest and destroy apoptotic oocytes? Somatic GCs ingest and destroy apoptotic oocytes and other apoptotic substrates through unconventional autophagy-assisted phagocytosis. Most (99%) ovarian germ cells undergo apoptosis through follicular atresia. The mode of cleaning of
Marta Pera et al.
The EMBO journal, 36(22), 3356-3371 (2017-10-12)
In the amyloidogenic pathway associated with Alzheimer disease (AD), the amyloid precursor protein (APP) is cleaved by β-secretase to generate a 99-aa C-terminal fragment (C99) that is then cleaved by γ-secretase to generate the β-amyloid (Aβ) found in senile plaques.
문서
Cellular oxidative stress is countered by enzymatic scavengers and antioxidant modulators against reactive oxygen species damage.
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