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Merck
모든 사진(1)

문서

24368C

SAFC

EX-CELL® Advanced CHO Feed 1 (without glucose)

의약품 제조

동의어(들):

EX-CELL® Advanced CHO Feed 1

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About This Item

UNSPSC 코드:
12352200
NACRES:
NA.71

제품 라인

EX-CELL®

Quality Level

형태

dry powder

기술

cell culture | mammalian: suitable (suspension)

배송 상태

ambient

저장 온도

2-8°C

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일반 설명

EX-CELL® Advanced CHO Feed 1 (without glucose) is chemically-defined and contains no animal derived components. This feed is intended to be a part of a fed-batch platform, and used with EX-CELL® Advanced CHO Fed-batch Medium (14366C or 24366C). This newest platform from SAFC has been specifically developed to support growth and productivity across a diverse set of Chinese Hamster Ovary (CHO) cells in fed-batch cultures while still allowing for flexibility in the adjustment of protein quality attributes. This contemporary fed-batch platform was developed using a strategy of Multivariate Analysis to establish correlations in which the formulation components influence critical process and product attributes such as titer, fold expansion, receptor expression, and glycosylation. This platform contains no hypoxanthine and thymidine, L-glutamine, phenol red or 2-mercaptoethanol (2-ME).

결합

Submit the EX-CELL Advanced CHO Fed-batch request form to get in touch with a SAFC representative.

수량

Formulated to contain 64.1 grams of powder per liter of medium.

법적 정보

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

관련 제품

제품 번호
설명
가격

픽토그램

CorrosionExclamation mark

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


시험 성적서(COA)

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문서 라이브러리 방문

Pao-Chun Lin et al.
mAbs, 11(5), 965-976 (2019-05-03)
Chinese hamster ovary (CHO) cells are the biopharmaceutical industry's primary means of manufacturing therapeutic proteins, including monoclonal antibodies. The major challenge in cell line development for the production of recombinant biopharmaceuticals lies in generating and isolating rare high-producing stable clones

문서

Optimizing feed for upstream cell culture improves monoclonal antibody production, but requires balancing outcomes for both viable cell density and productivity.

In this study, nine commercially available, chemically defined media and feed combinations from different vendors were assessed for producing monoclonal antibody in Chinese hamster ovary (CHO) cells.

Our step-by-step guide to optimizing media and feed combinations for upstream bioprocessing.

Cell culture media are vital for bioprocessing therapeutics. This page describes the central role of our organization in authoring purpose-built GMP for cell culture media.

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Eliminate the need to clean, autoclave and assemble your traditional glass bioreactors and save days of downtime with the Mobius® 3L Single-use Bioreactor.

Learn more about cell culture media development for mAB development and manufacturing, and the products you need for this step.

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