475R-9

INSM1 (MRQ-70) Rabbit Monoclonal Antibody

• 동의어(들): Insulinoma-associated protein 1
• UNSPSC 코드: 12352203
• 클론: MRQ-70, monoclonal
• application: IHC (p)
• 종 반응성: human
• 기술: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• citations: 6

속성

• 생물학적 소스: rabbit
• Quality Level: 100; 500
• 결합: unconjugated
• 항체 형태: culture supernatant
• 항체 생산 유형: primary antibodies
• 클론: MRQ-70, monoclonal
• 설명: For In Vitro Diagnostic Use in Select Regions
• 양식: buffered aqueous solution
• 종 반응성: human
• 포장: vial of 0.1 mL concentrate (475R-94); vial of 0.1 mL concentrate Research Use Only (475R-94-RUO); vial of 0.5 mL concentrate (475R-95); vial of 1.0 mL concentrate (475R-96); vial of 1.0 mL concentrate Research Use Only (475R-96-RUO); vial of 1.0 mL pre-dilute Research Use Only (475R-97-RUO); vial of 1.0 mL pre-dilute ready-to-use (475R-97); vial of 7.0 mL pre-dilute ready-to-use (475R-98); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (475R-98-RUO)
• 제조업체/상표: Cell Marque^™
• 기술: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• 동형: IgG
• 제어: pancreas
• 배송 상태: wet ice
• 저장 온도: 2-8°C
• 시각화: nuclear

설명

일반 설명

Insulinoma-associated protein 1 (INSM1) is a transcriptional factor with a zinc finger DNA-binding domain that is involved in neuroendocrine cell differentiation as a transcriptional repressor¹. INSM1 expression has been observed during embryonic development in the cerebellum, spinal cord, olfactory epithelium, pancreas, and gastrointestinal tract^2-4; however, expression in healthy adult tissues is limited to neuroendocrine cells. INSM1 is over expressed in neuroendocrine neoplasms including carcinoids, small cell carcinomas, and neuroendocrine carcinomas. This helps in identification of neuroendocrine tumors and their distinction from other lesions, such as adenocarcinomas, which exhibit little to no INSM1 expression^5-6.

품질

United States - IVD
Canada - RUO
European Union - IVD
Japan - RUO

물리적 형태

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

제조 메모

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기타 정보

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

법적 정보

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable