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Merck
모든 사진(1)

주요 문서

82415

Sigma-Aldrich

Prunetin

≥98.0% (TLC)

동의어(들):

4′,5-Dihydroxy-7-methoxyisoflavone

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About This Item

실험식(Hill 표기법):
C16H12O5
CAS Number:
Molecular Weight:
284.26
Beilstein:
292155
EC Number:
MDL number:
UNSPSC 코드:
51111800
PubChem Substance ID:
NACRES:
NA.77

Quality Level

분석

≥98.0% (TLC)

양식

powder

SMILES string

COc1cc(O)c2C(=O)C(=COc2c1)c3ccc(O)cc3

InChI

1S/C16H12O5/c1-20-11-6-13(18)15-14(7-11)21-8-12(16(15)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3

InChI key

KQMVAGISDHMXJJ-UHFFFAOYSA-N

생화학적/생리학적 작용

Inhibitor of both cytoplasmic and mitochondrial human liver aldehyde dehydrogenases, possibly by binding at an allosteric site.

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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시험 성적서(COA)

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문서 라이브러리 방문

M L Shen et al.
Journal of the American Society for Mass Spectrometry, 12(1), 97-104 (2001-01-06)
Aldehyde dehydrogenases (ALDH) are a family of enzymes primarily involved in the oxidation of various aldehydes. Most ALDH enzymes derived from mammalian sources have been shown to exist as homotetramers, consisting of four identical subunits of approximately 54 kDa. The
Tae-Gue Ahn et al.
Biochemical pharmacology, 85(10), 1525-1533 (2013-02-27)
Prunetin is an O-methylated isoflavone, which is a type of flavonoid. There are a limited number of reports detailing the biological activities of prunetin. Although an anti-inflammatory effect of prunetin has been reported in vitro, to our knowledge, there have
Soon-Sen Leow et al.
Experimental gerontology, 106, 198-221 (2018-03-20)
Palm fruit juice (PFJ) containing oil palm phenolics is obtained as a by-product from oil palm (Elaeis guineensis) fruit milling. It contains shikimic acid, soluble fibre and various phenolic acids including p-hydroxybenzoic acid and three caffeoylshikimic acid isomers. PFJ has
Hyun Jae Lee et al.
Phytotherapy research : PTR, 25(8), 1196-1200 (2011-02-10)
This study investigated whether prunetin significantly affects the secretion, production and gene expression of mucin from cultured airway epithelial cells. Confluent primary rat tracheal surface epithelial (RTSE) cells were pretreated with adenosine triphosphate (ATP) for 5 min and then chased for
Stephen W J Wang et al.
The Journal of pharmacology and experimental therapeutics, 329(3), 1023-1031 (2009-03-07)
Flavonoids have poor bioavailabilities largely because of metabolism via UDP-glucuronosyltransferases (UGTs). This study aims to further understand the functions of UGT in metabolizing genistein and apigenin, two compounds metabolized more extensively in the gut than in the liver. Because Gunn

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