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Merck
모든 사진(1)

주요 문서

86614

Sigma-Aldrich

Tetraethylammonium chloride

BioUltra, for molecular biology, ≥99.0% (AT)

동의어(들):

Etamon chloride, TEAC, TEA chloride

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About This Item

Linear Formula:
(C2H5)4N(Cl)
CAS Number:
Molecular Weight:
165.70
Beilstein:
3563247
EC Number:
MDL number:
UNSPSC 코드:
12352107
PubChem Substance ID:
NACRES:
NA.26

Grade

for molecular biology

Quality Level

제품 라인

BioUltra

분석

≥99.0% (AT)

형태

powder

분자량

165.70 g/mol

기술

gas chromatography (GC): suitable

불순물

DNases, none detected
RNases, none detected
insoluble matter, passes filter test
phosphatases, none detected
proteases, none detected

solubility

H2O: 1 M at 20 °C, clear, colorless

음이온 미량물

bromide (Br-): ≤500 mg/kg
sulfate (SO42-): ≤50 mg/kg

양이온 미량물

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

1 M in H2O

UV 흡수

λ: 260 nm Amax: 0.03
λ: 280 nm Amax: 0.03

SMILES string

[Cl-].CC[N+](CC)(CC)CC

InChI

1S/C8H20N.ClH/c1-5-9(6-2,7-3)8-4;/h5-8H2,1-4H3;1H/q+1;/p-1

InChI key

YMBCJWGVCUEGHA-UHFFFAOYSA-M

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일반 설명

Tetraethylammonium (TEA), a simple quaternary ammonium compound, is commonly used to block potassium channels. It can physically enter the pore and block the channel. Additionally, TEA either imitates or antagonizes the actions of choline and acetylcholine, two other quaternary ammonium ions.

애플리케이션

Tetraethylammonium chloride has been used:

  • as a pharmacological agent in electrophysiology to study its pharmacological effects on Cnidarians
  • as a component in refolding buffer for protein refolding
  • to puff onto isolated patches to block voltage-gated K+ (Kv3) channels and post-hoc evaluation

특징 및 장점

  • Assay: ≥99.0% (AT), BioUltra, for molecular biology
  • Suitable for gas chromatography (GC)

기타 정보

TEACl method of DNA-DNA hybridization

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

201.2 °F - closed cup

Flash Point (°C)

94 °C - closed cup

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

Tetraethylammonium
Simmons MA
xPharm: The Comprehensive Pharmacology Reference, 1-3 (2007)
A. Caccone et al.
NATO ASI Ser., Ser H, 57, 385-385 (1991)
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eLife, 11 (2022-06-22)
In Alzheimer's disease (AD), a multitude of genetic risk factors and early biomarkers are known. Nevertheless, the causal factors responsible for initiating cognitive decline in AD remain controversial. Toxic plaques and tangles correlate with progressive neuropathology, yet disruptions in circuit
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Structure (London, England : 1993), 26(9), 1210-1225 (2018-07-24)
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