모든 사진(3)
About This Item
실험식(Hill 표기법):
C15H18O2
CAS Number:
Molecular Weight:
230.30
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.25
추천 제품
Quality Level
분석
≥98% (HPLC)
형태
powder or crystals
solubility
methanol: 1 mg/mL, clear, colorless
응용 분야
metabolomics
vitamins, nutraceuticals, and natural products
저장 온도
2-8°C
SMILES string
C=C1CCC[C@@](C=C2O3)(C)[C@@]1([H])CC2=C(C)C3=O
InChI
1S/C15H18O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h8,12H,1,4-7H2,2-3H3/t12-,15+/m0/s1
InChI key
ZTVSGQPHMUYCRS-SWLSCSKDSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
Atractylenolide I is one of the active ingredients of Rhizoma Atractylodes macrocephala which is obtained from the dried root and stem of Atractylodes Macrocephala Koidz. It is a sesquiterpene compound of hydrophobic nature.
애플리케이션
Atractylenolide I is a phytochemical that may be used to study its anti-inflammatory and anti-angiogenesis activities. Atractylenolide I may be used and studied as a postitive modulator of GABA-induced chloride currents I(GABA) and as an inhibitor of aromatases. Atractylenolide I may be used as a reference material in assays to detect its presence in plant root extracts and biological milieu such as plasma.
생화학적/생리학적 작용
Atractylenolide I has been reported to have an anti-inflammatory activity due to its inhibitory effect on tumor necrosis factor-α (TNF-α) and the production of nitric oxide (NO). It also shows anti-cancer nature, thereby being used in the management of gastric cancer cachexia symptoms. Additionally, it has anti-angiogenic, pro-oxidative and cytotoxic characteristics.
Phytochemical from Traditional Chinese Medicine herbal preparations. Atractylenolide I is an anti-inflammatory that is reported to inhibit angiogenesis.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
339.6 °F
Flash Point (°C)
170.87 °C
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Hyun Young Park et al.
Planta medica, 77(13), 1528-1530 (2011-02-25)
The roots of Cyathula officinalis Kuan are widely used in Chinese medicine for the treatment of inflammatory disorders. Here, the ability of C. officinalis Kuan to downregulate matrix metalloproteinase (MMP)-13 was examined since MMP-13 is an important enzyme for the
Ching-Chiung Wang et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 44(8), 1308-1315 (2006-04-21)
The dried rhizome of Bai Zhu (Atractylodes ovata) is widely used as a Chinese herbal medicine. Two sesquiterpenolides of similar structures (atractylenolide I, AT-I; atractylenolide III, AT-III) were isolated from dried rhizome of Atractylodes ovata. Incubation of AT-I with recombinant
Judith Singhuber et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 19(3-4), 334-340 (2011-11-29)
Several Chinese herbal medicines (CHMs) are used in the treatment of insomnia, restlessness, or anxiety. However, mechanisms underlying this effect and scientific proof for their traditional use is scarce. In the present study CHMs were screened for their ability to
Yi Liu et al.
Evidence-based complementary and alternative medicine : eCAM, 5(3), 337-344 (2008-10-03)
We determined the therapeutic efficacy of atractylenolide I (ATR), extracted from largehead atractylodes rhizome, in managing gastric cancer cachexia (GCC), and interpreted its probable pharmacological mechanism via investigating tumor necrosis factor alpha (TNF-alpha), interleukin-1 (IL-1), interleukin-6 (IL-6) and proteolysis-inducing factor
Jian-Ming Huang et al.
Scientific reports, 4, 3840-3840 (2014-01-24)
Paclitaxel, a known TLR4 ligand, leads to activation of TLR4/MyD88-dependent pathway that mediates chemoresistance and tumor progression in epithelial ovarian carcinoma (EOC). Atractylenolide-I (AO-I), a novel TLR4-antagonizing agent, inhibits TLR4 signaling by interfering with the binding of LPS or paclitaxel
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