A3509

2-Aminopurine

≥99%, synthetic, powder

• 동의어(들): 2-AP
• 실험식(Hill 표기법): C₅H₅N₅
• CAS 번호: 452-06-2
• Molecular Weight: 135.13
• EC Number: 207-197-4
• MDL number: MFCD00005566
• UNSPSC 코드: 41106305
• PubChem Substance ID: 24890778
• NACRES: NA.51

속성

• 제품 이름: 2-Aminopurine, ≥99%
• 생물학적 소스: synthetic
• Quality Level: 200
• 분석: ≥99%
• 양식: powder
• mp: 280-282 °C (lit.)
• 저장 온도: 2-8°C
• SMILES string: Nc1ncc2[nH]cnc2n1
• InChI: 1S/C5H5N5/c6-5-7-1-3-4(10-5)9-2-8-3/h1-2H,(H3,6,7,8,9,10)
• InChI key: MWBWWFOAEOYUST-UHFFFAOYSA-N

설명

애플리케이션

2-Aminopurine (2-AP) is used to specifically inhibit double-stranded RNA-dependent protein kinase, protein kinase R (PKR).

2-Aminopurine has been used to inhibit eukaryotic initiation factor-2α (eIF2α)-phosphorylation of osteoarthritis (OA) chondrocytes.

생화학적/생리학적 작용

2-Aminopurine (2AP) is an analog of guanosine and adenosine, which can base pair with cytosine and thymine. It is used as a fluorescent probe in nucleic acid structure and dynamics. 2-Aminopurine (2-AP) inhibits double-stranded RNA-dependent protein kinase, protein kinase R (PKR).

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves