A7687

Aloe-emodin

≥95% (HPLC)

• 동의어(들): 1,8-Dihydroxy 3-hydroxymethylanthraquinone, 1,8-Dihydroxy-3-(hydroxymethyl)anthraquinone, 3-Hydroxymethylchrysazine, Rhabarberone
• 실험식(Hill 표기법): C₁₅H₁₀O₅
• CAS Number: 481-72-1
• Molecular Weight: 270.24
• Beilstein: 2059062
• EC Number: 207-571-7
• MDL number: MFCD00017373
• UNSPSC 코드: 12352205
• PubChem Substance ID: 24891267
• NACRES: NA.79

속성

• 생물학적 소스: plant root (Rheum palmatum)
• Quality Level: 200
• 분석: ≥95% (HPLC)
• 양식: powder
• 기술: HPLC: suitable
• 색상: yellow to brown
• 저장 온도: 2-8°C
• SMILES string: OCc1cc(O)c2C(=O)c3c(O)cccc3C(=O)c2c1
• InChI: 1S/C15H10O5/c16-6-7-4-9-13(11(18)5-7)15(20)12-8(14(9)19)2-1-3-10(12)17/h1-5,16-18H,6H2
• InChI key: YDQWDHRMZQUTBA-UHFFFAOYSA-N

설명

일반 설명

Aloe-emodin is a hydroxyanthraquinone found naturally in aloe plants.

애플리케이션

Aloe-emodin has been used as a standard in high performance liquid chromatography (HPLC) for separation and identification of phenolic compounds in Aloe arborescens Miller var. natalensis Berger (Kidachi aloe).

생화학적/생리학적 작용

Aloe-emodin exhibits antibacterial, antiviral, anti-inflammatory and hepatoprotective effects.

Laxative/cathartic compound; increases the contraction of intestinal smooth muscle by releasing endogenous acetylcholine. Anti-tumor activity is associated with an increased production of reactive oxygen species (ROS) that, in turn, reduces the mitochondrial transmembrane electrical potential, thus inducing a permeability transition that sets in motion a series of events culminating in cellular apoptosis. Genotoxicity and mutagenicity appear to be due to the inhibition of topoisomerase II activity by aloe emodin.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves