B1436

BAX Inhibiting Peptide V5

≥97% (HPLC), lyophilized powder

• 동의어(들): BIP-V5
• 실험식(Hill 표기법): C₂₇H₅₀N₆O₆S
• CAS Number: 579492-81-2
• Molecular Weight: 586.79
• MDL number: MFCD04974826
• UNSPSC 코드: 12352200
• NACRES: NA.32

속성

• Quality Level: 200
• 분석: ≥97% (HPLC)
• 양식: lyophilized powder
• 저장 온도: −20°C
• SMILES string: S(CC[C@H](NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O)C
• InChI: 1S/C27H50N6O6S/c1-16(2)15-20(24(35)31-19(27(38)39)9-6-7-12-28)32-23(34)18(11-14-40-5)30-25(36)21-10-8-13-33(21)26(37)22(29)17(3)4/h16-22H,6-15,28-29H2,1-5H3,(H,30,36)(H,31,35)(H,32,34)(H,38,39)/t18-,19-,20-,21-,22-/m0/s1
• InChI key: NHMUTADCTDDWPV-YFNVTMOMSA-N

설명

Amino Acid Sequence

Val-Pro-Met-Leu-Lys

생화학적/생리학적 작용

BAX Inhibiting Peptide V5 protects Bax against conformational changes and it also prevents mitochondrial translocation. In vitro analysis prove that peptide V5 prevents apoptosis, mediated by a number of agents including staurosporine, ultraviolet and anti-cancer drug.

Bax-mediated apoptosis inhibitor; membrane permeable pentapeptide based on the Ku70-Bax inhibiting domain.

기타 정보

Lyophilized from 0.1% TFA in H2O

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)