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Merck
모든 사진(1)

주요 문서

C0567

Sigma-Aldrich

(−)-Catechin

from green tea, ≥97% (HPLC), powder, oxidative stress inhibitor

동의어(들):

(−)-trans-3,3′,4′,5,7-Pentahydroxyflavane, (2S,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol

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About This Item

실험식(Hill 표기법):
C15H14O6
CAS Number:
Molecular Weight:
290.27
EC Number:
MDL number:
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.77

제품명

(−)-Catechin, ≥97% (HPLC), from green tea

생물학적 소스

green tea

Quality Level

분석

≥97% (HPLC)

양식

powder

저장 온도

2-8°C

SMILES string

O[C@@H]1Cc2c(O)cc(O)cc2O[C@H]1c3ccc(O)c(O)c3

InChI

1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15+/m1/s1

InChI key

PFTAWBLQPZVEMU-HIFRSBDPSA-N

유전자 정보

human ... BACE1(23621)

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일반 설명

Catechins are major flavonoids present in green tea accounting to 90%. (−)-catechin is comparatively less bioavailable than the (+)-catechin for intestinal absorption.

애플리케이션

(-)-Catechin has been used:
  • to test its binding affinity towards estrogen receptor
  • as a reference standard in high-performance liquid chromatography for quantification of polyphenols from plant extracts (HPLC)
  • as a reference standard in kinetic studies to quantify antioxidants from Iranian green tea leaves

생화학적/생리학적 작용

Catechins have wide biological functionality. They induce antiviral and anticancer activities. Catechins also play a key role in regulating carbohydrate and lipid metabolism. It prevents fat accumulation.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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시험 성적서(COA)

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Estrogen-like effects of wine extracts on nitric oxide synthesis in human endothelial cells
Simoncini T, et al.
Maturitas, 70(2), 169-175 (2011)
Green tea catechins: Their use in treating and preventing infectious diseases
Reygaert WC
BioMed Research International, 2018 (2018)
Rajapandiyan Krishnamoorthy et al.
Biomolecules, 9(12) (2019-12-11)
Human gut microbes are a profitable tool for the modification of food compounds into biologically active metabolites. The biological properties of catechins have been extensively investigated. However, the bioavailability of catechin in human blood plasma is very low. This study
Ji Hyung Jun et al.
Nature plants, 4(12), 1034-1043 (2018-11-28)
Proanthocyanidins (PAs) are primarily composed of the flavan-3-ol subunits (-)-epicatechin and/or (+)-catechin, but the basis for their different starter and extension unit compositions remains unclear. Genetic and biochemical analyses show that, in the model legume Medicago truncatula, two 2-oxoglutarate-dependent dioxygenases
(+)-Catechin is more bioavailable than (-)-catechin: relevance to the bioavailability of catechin from cocoa
Donovan JL, et al.
Free Radical Research, 40(10), 1029-1034 (2006)

문서

DISCOVER Bioactive Small Molecules for Nitric Oxide & Cell Stress Research

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