C1240

Chlormethiazole hydrochloride

≥98% (HPLC), powder

• 동의어(들): 4-methyl-5-(β-chloroethyl)thiazole hydrochloride, 5-(2-Chloroethyl)-4-methylthiazole hydrochloride, Clomethiazole hydrochloride, Somnevrin hydrochloride
• 실험식(Hill 표기법): C₆H₈ClNS · HCl
• CAS Number: 6001-74-7
• Molecular Weight: 198.11
• MDL number: MFCD00673948
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329774745
• NACRES: NA.77

속성

• 설명: Store desiccated
• Quality Level: 100
• 분석: ≥98% (HPLC)
• 형태: powder
• 색상: off-white
• solubility: H₂O: soluble >10 mg/mL
• 주관자: AstraZeneca
• SMILES string: Cl.Cc1ncsc1CCCl
• InChI: 1S/C6H8ClNS.ClH/c1-5-6(2-3-7)9-4-8-5;/h4H,2-3H2,1H3;1H
• InChI key: OFXYKSLKNMTBHK-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

Chlormethiazole serves as an anticonvulsant. It is useful in treating alcohol addiction and eclampsia. Chlormethiazole is also useful in treating convulsive status epilepticus. Long term administration of chlormethiazole leads to addiction to the drug.

GABA_A agonist; glycine receptor modulator.

특징 및 장점

This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H302,H317,H318
• 예방조치 성명서: P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Faceshields, Gloves