C1254

Sodium cholate hydrate

from bovine and/or ovine bile, ≥99%

• 동의어(들): 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt, Cholalic acid sodium salt
• 실험식(Hill 표기법): C₂₄H₃₉NaO₅ · xH₂O
• CAS Number: 206986-87-0
• Molecular Weight: 430.55 (anhydrous basis)
• Beilstein: 3582354
• EC Number: 206-643-5
• MDL number: MFCD00150749
• UNSPSC 코드: 12161900
• PubChem Substance ID: 24892390
• NACRES: NA.25

속성

• 생물학적 소스: bovine and/or ovine bile
• 설명: anionic
• 분석: ≥99%
• 형태: powder
• 분자량: micellar avg mol wt 900-1300
• 응집 번호: 2-3
• 기술: DNA purification: suitable; RNA purification: suitable; western blot: suitable
• CMC: 9-15 mM (20-25°C)
• solubility: water: 100 mg/mL, clear, colorless to light yellow
• HLB: 18
• SMILES string: O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3[C@H](O)CC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C
• InChI: 1S/C24H40O5.Na.H2O/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26;;/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29);;1H2/q;+1;/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-;;/m1../s1
• InChI key: MUVVIYFKOVLQHL-RCVKHMDESA-M

설명

일반 설명

Sodium cholate hydrate, a non-denaturing anionic detergent, plays a crucial role in biochemical research, particularly in protein solubilization and membrane permeabilization, making it essential for protein extraction and purification, especially when dealing with membrane proteins and protein complexes. Derived from cholic acid, a prevalent human bile acid, sodium cholate hydrate′s water solubility and its applications extend to investigating the effects of various substances on cell cultures, making it a versatile tool in laboratory research.

애플리케이션

Sodium cholate hydrate has been used in a study to assess the effect of phospholipid formulation and surfactants on the dermal delivery of hydrophilic drugs from elastic liposomes. It has also been used in a study to investigate the elastic deformable vesicles, transfersomes, for transdermal drug delivery.

생화학적/생리학적 작용

Bile Salt

특징 및 장점

• Suitable for Western blotting
• Suitable for DNA and RNA purification
• High purity product for research applications

기타 정보

For additional information on our range of Biochemicals, please complete this form.

안전성 정보

• 유해 및 위험 성명서: H412
• 예방조치 성명서: P273 - P501
• Hazard Classifications: Aquatic Chronic 3
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)