D3669
3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester)
powder
동의어(들):
DTSP, Di(N-succinimidyl) 3,3′-dithiodipropionate, Dithiobis(succinimidyl propionate), Lomant’s reagent
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
실험식(Hill 표기법):
C14H16N2O8S2
CAS Number:
Molecular Weight:
404.42
Beilstein:
1518074
EC Number:
MDL number:
UNSPSC 코드:
12352106
PubChem Substance ID:
NACRES:
NC.07
추천 제품
양식
powder
Quality Level
반응 적합성
reagent type: cross-linking reagent
solubility
chloroform: 50 mg/mL
DMF: soluble
acetone: soluble
저장 온도
−20°C
SMILES string
O=C(CCSSCCC(=O)ON1C(=O)CCC1=O)ON2C(=O)CCC2=O
InChI
1S/C14H16N2O8S2/c17-9-1-2-10(18)15(9)23-13(21)5-7-25-26-8-6-14(22)24-16-11(19)3-4-12(16)20/h1-8H2
InChI key
FXYPGCIGRDZWNR-UHFFFAOYSA-N
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일반 설명
3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) (DSP) is a homobifunctional cross-linking reagent containing a cleavable disulfide linkage. It is typically coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5).
애플리케이션
3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) (DSP) has been used as a protein cross-linker.
특징 및 장점
The disulfide linkage is cleavable by mild reduction.
주의사항
Avoid use of reducing agents during coupling reactions.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
이미 열람한 고객
M Darder et al.
Analytical chemistry, 71(24), 5530-5537 (2000-01-07)
Exposure of gold surfaces to solutions of dithiobis N-succinimidyl propionate (DTSP) gives rise to the modification of the surface with N-succinimidyl-3-thiopropionate (NSTP) which can, in turn, react with amino groups allowing for the covalent immobilization of enzymes such as horseradish
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The Analyst, 136(3), 486-492 (2010-11-17)
A bioassay platform using T4 bacteriophage (T4) as the specific receptor and surface plasmon resonance (SPR) as the transduction technique has been developed for the detection of Escherichia coli K12 bacteria. The T4 phages have been covalently immobilized onto gold
M Gamero et al.
Biosensors & bioelectronics, 25(9), 2038-2044 (2010-02-23)
The design and characterization of a lactate biosensor using a nanostructured rough gold surface as a transducer is reported. The biosensor is developed by immobilization of lactate oxidase (LOx), on a rough gold electrode modified with a self-assembled monolayer of
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