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Merck
모든 사진(3)

주요 문서

D6898

Sigma-Aldrich

Deoxyribonucleic acid sodium salt from herring testes

Type XIV

동의어(들):

DNA

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About This Item

CAS Number:
MDL number:
UNSPSC 코드:
41106305
eCl@ss:
32160414
NACRES:
NA.51

유형

Type XIV

Quality Level

형태

solid

저장 온도

2-8°C

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일반 설명

Deoxyribonucleic acid sodium salt from herring testes, also known as HtDNA is a natural source of DNA designed for DNA binding agent studies. The detection limits of HtDNA are around 5.0ng and linear ranges of light scattering intensity (I(LS)) is 0.05-2.5 mµg.

애플리케이션

Deoxyribonucleic acid sodium salt from herring testes is used in studies of DNA binding agents that modulate DNA structure and function. Herring testes DNA is also used in physicochemical studies of DNA behavior in solution.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

X Du et al.
Talanta, 55(1), 93-98 (2008-10-31)
The interaction of histone with nucleic acids was characterized by light-scattering measurement using a common spectrofluorometer. Thereby, a sensitive and convenient method for the determination of nucleic acids was established. At pH 4.5-6.5, the interaction of histone with nucleic acids
Renée M Van der Sluis et al.
PLoS pathogens, 16(2), e1008151-e1008151 (2020-02-29)
HIV latency is the major barrier to a cure for people living with HIV (PLWH) on antiretroviral therapy (ART) because the virus persists in long-lived non-proliferating and proliferating latently infected CD4+ T cells. Latently infected CD4+ T cells do not
Assaf Marcus et al.
Immunity, 49(4), 754-763 (2018-10-18)
Detection of cytosolic DNA by the enzyme cGAS triggers the production of cGAMP, a second messenger that binds and activates the adaptor protein STING, which leads to interferon (IFN) production. Here, we found that in vivo natural killer (NK) cell killing
Larisa I Labzin et al.
The EMBO journal, 38(21), e101365-e101365 (2019-08-31)
Inflammasomes are potent innate immune signalling complexes that couple cytokine release with pro-inflammatory cell death. However, pathogens have evolved strategies to evade this cell autonomous system. Here, we show how antibodies combine with innate sensors in primary human macrophages to
K L Jønsson et al.
Nature communications, 8, 14391-14391 (2017-02-12)
Innate immune activation by macrophages is an essential part of host defence against infection. Cytosolic recognition of microbial DNA in macrophages leads to induction of interferons and cytokines through activation of cyclic GMP-AMP synthase (cGAS) and stimulator of interferon genes

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