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Merck
모든 사진(2)

문서

D7250

Sigma-Aldrich

2′-Deoxycytidine 5′-diphosphate sodium salt

≥96%

동의어(들):

dCDP

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About This Item

실험식(Hill 표기법):
C9H15N3O10P2 · xNa+
CAS Number:
Molecular Weight:
387.18 (free acid basis)
MDL number:
UNSPSC 코드:
41106305
PubChem Substance ID:
NACRES:
NA.51

Quality Level

분석

≥96%

형태

powder

저장 온도

−20°C

SMILES string

O.[Na].NC1=NC(=O)N(C=C1)C2CC(O)C(COP(O)(=O)OP(O)(O)=O)O2

InChI

1S/C9H15N3O10P2.Na.H2O.H/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(21-8)4-20-24(18,19)22-23(15,16)17;;;/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H2,10,11,14)(H2,15,16,17);;1H2;

InChI key

MNOALMYIRLFAQW-UHFFFAOYSA-N

관련 카테고리

애플리케이션

2′-Deoxycytidine 5′-diphosphate (dCDP) has been used as a substrate for nucleotide diphosphate kinase (NDPK) to produce 2′-deoxycytidine 5′-triphosphate (dCTP) in support of DNA biosynthesis and reverse transcription.

픽토그램

Skull and crossbones

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

High glucose triggers nucleotide imbalance through O-GlcNAcylation of key enzymes and induces KRAS mutation in pancreatic cells
Hu CM, et al.
Cell Metabolism, 29(6), 1334-1349 (2019)
Hüseyin Besir et al.
FEBS letters, 579(29), 6595-6600 (2005-11-19)
Nucleoside diphosphate kinase from the halophilic archaeon Halobacterium salinarum was crystallized in a free state and a substrate-bound form with CDP. The structures were solved to a resolution of 2.35 and 2.2A, respectively. Crystals with the apo-form were obtained with
Argirios Siskos et al.
Journal of plant physiology, 167(9), 675-682 (2010-03-02)
Two isoforms of NDPKs (diphosphonucleoside kinases: E.C. 2.7.4.6.) named S-NDPK-A and S-NDPK-B were separated and purified from shoots of Alyssum murale (19th day of growth), a nickel accumulator plant, by a four-step procedure involving ammonium sulphate precipitation and DEAE-sepharose and
Mahmoud Kandeel et al.
Journal of bioenergetics and biomembranes, 42(5), 361-369 (2010-08-17)
Nucleoside diphosphate kinases (NDKs) play a key role in maintaining the intracellular energy resources as well as the balance of nucleotide pools. Recently, attention has been directed to NDKs owing to its role in activating various chemotherapeutic agents. The binding
Dimitri Topalis et al.
Nucleosides, nucleotides & nucleic acids, 26(10-12), 1369-1373 (2007-12-11)
Human UMP-CMP kinase is involved in the phosphorylation of nucleic acid precursors and also in the activation of antiviral analogues including cidofovir, an acyclic phosphonate compound that mimicks dCMP and shows a broad antiviral spectrum. The binding of ligands to

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