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Merck
모든 사진(1)

주요 문서

F3301

Sigma-Aldrich

Factor Xa chromogenic substrate

chromogenic, ≥90% (HPLC), solid

동의어(들):

CH3OCO-D-CHA-Gly-Arg-pNA-AcOH

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About This Item

MDL number:
UNSPSC 코드:
12352204
NACRES:
NA.83

product name

Factor Xa chromogenic substrate, solid

분석

≥90% (HPLC)

Quality Level

형태

solid

분자량

apparent mol wt 622.7

solubility

methanol: water (1:9): 25 mg/mL

저장 온도

2-8°C

애플리케이션

Factor Xa chromogenic substrate has been used in factor Xa protease assay for placenta organelle protein and Prospirobolus joannsi.

생화학적/생리학적 작용

Factor Xa chromogenic substrate contains peptide sequence Bz-Ile-Glu-Gly-Arg-pNA. Factor Xa mediates the release of p-NA chromogen post hydrolysis of substrate which is measurable photometrically.

물리적 특성

KM for human factor Xa is ~0.8mM

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

Probing substrate-induced conformational alterations in adrenoleukodystrophy protein by proteolysis
Guimaraes CP, et al.
Journal of Human Genetics, 50(2), 99-99 (2005)
Zilei Duan et al.
Cellular and molecular life sciences : CMLS, 79(6), 309-309 (2022-05-22)
Blood clot formation induced by dysfunctional coagulation is a frequent complication of coronavirus disease 2019 (COVID-19) and a high-risk factor for severe illness and death. Neutrophil extracellular traps (NETs) are implicated in COVID-19-induced immunothrombosis. Furthermore, human cathelicidin, a NET component
Joannsin, a novel Kunitz-type FXa inhibitor from the venom of Prospirobolus joannsi
Luan N, et al.
Thrombosis and Haemostasis, 117(06), 1031-1039 (2017)
Pathology consultation on anticoagulation monitoring: factor X-related assays
Wool GD and Lu CM
American Journal of Clinical Pathology, 140(5), 623-634 (2013)
Ning Luan et al.
Thrombosis and haemostasis, 117(6), 1031-1039 (2017-03-10)
The repugnatorial glands of millipedes release various defensive chemical secretions. Although varieties of such defensive secretions have been studied, none of them is protein or peptide. Herein, a novel factor Xa (FXa) inhibitor named joannsin was identified and characterised from repugnatorial glands

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