G0759

Sodium glycochenodeoxycholate

• 동의어(들): 3α,7α-Dihydroxy-5β-cholanoic acid N-(carboxymethyl)amide sodium salt, Glycochenodeoxycholic acid sodium salt, N-(3α,7α-Dihydroxy-24-oxocholan-24-yl)glycine sodium salt
• 실험식(Hill 표기법): C₂₆H₄₂NNaO₅
• CAS Number: 16564-43-5
• Molecular Weight: 471.61
• Beilstein: 3847290
• MDL number: MFCD00036743
• UNSPSC 코드: 12161900
• PubChem Substance ID: 24895023
• NACRES: NA.25

속성

• 설명: anionic
• Quality Level: 200
• 양식: powder
• 분자량: 471.61 g/mol
• 기술: HPLC: suitable; protein quantification: suitable
• 작용기: sulfonic acid
• 배송 상태: ambient
• 저장 온도: room temp
• SMILES string: [Na+].C[C@H](CCC(=O)NCC([O-])=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C26H43NO5.Na/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29;/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32);/q;+1/p-1/t15-,16+,17-,18-,19+,20+,21-,24+,25+,26-;/m1./s1
• InChI key: AAYACJGHNRIFCT-YRJJIGPTSA-M

설명

일반 설명

Glycochenodeoxycholate (GCDC) is a toxic hydrophobic bile salt.

애플리케이션

Sodium glycochenodeoxycholate has been used as an additive in de Man, Rogosa and Sharpe (MRS) agar for bile acid deconjugation to determine the capacity of the strains to deconjugate specific bile acids.

Sodium glycochenodeoxycholate has been used in a study to assess the repair of DNA damage induced by bile salts. It has also been used in a study to investigate enterotoxin production by Clostridium perfringens type A in the presence of human bile salts.

생화학적/생리학적 작용

Glycochenodeoxycholate (GCDC) can induce hepatocyte apoptosis that is partially mediated by Fas.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)