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Merck
모든 사진(5)

문서

G5009

Sigma-Aldrich

γ-Globulins from bovine blood

≥99% (agarose gel electrophoresis)

동의어(들):

Bovine γ-Globulin

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC 코드:
12352202
NACRES:
NA.61

생물학적 소스

bovine blood

분석

≥99% (agarose gel electrophoresis)

형태

powder

구성

NaCl, ≤4%

기술

enzyme immunoassay: suitable

solubility

0.9% NaCl: soluble 25 mg/mL

저장 온도

−20°C

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일반 설명

Bovine gamma globulin (BGG) is an important component of the immune system of cows and other bovines. BGG is found in the blood of bovines and is primarily used in the production of medical products such as vaccines, serums, and diagnostic reagents. BGG can also be used to treat certain medical conditions, such as hepatitis B, as well as to boost immunity in humans and other animals.

애플리케이션

Bovine γ-globulins were used to study the constituents and pH changes in protein rich hyaluronan solution which affect the biological properties of artificial articular joints. It is also used to determine immunoglobulin G in bovine colostrum and milk using direct biosensor SPR-immunoassay.
Bovine γ-globulin has been used as an immunological challenge in studies of mechanisms of immunotolerance.

생화학적/생리학적 작용

The γ-G globulins of bovine serum are categorized by anion exchange chromatography, immunoelectrophoresis, zone electrophoresis, ultracentrifugation, and analysis of the products of papain digestion. They have properties similar to analogous components of human serum. This was determined by the methods such as: gel filtration, immunoelectrophoresis, anion exchange chromatography, ultracentrifugation, and reduction with mercaptoethanol. Fast and slow γ-G globulins were classified on the basis of differences in electrophoretic migration rates, chromatographic elution positions, and biological activities (complement fixation). Bovine γ-A was conditionally found in immunoelectrophoretic analyses of serum and chromatographic fractions.

제조 메모

Prepared from Cohn Fraction II, III

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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Physical heterogeneity of bovine gamma-globulins: characterization of gamma-M and gamma-G globulins.
F A Murphy et al.
Archives of biochemistry and biophysics, 112(1), 126-136 (1965-10-01)
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