G5640

Globulins Cohn fraction II, III from goat

• 동의어(들): Vitamin D binding protein
• CAS Number: 68476-36-8
• EC Number: 270-678-2
• MDL number: MFCD00164084
• UNSPSC 코드: 12352202
• NACRES: NA.61

속성

• 생물학적 소스: goat
• Quality Level: 300
• 분석: 73-90% protein basis (biuret)
• 양식: lyophilized powder
• 구성: Protein, 73-90% biuret
• solubility: H₂O: soluble 25 mg/mL
• 저장 온도: 2-8°C

설명

일반 설명

Vitamin D binding protein (DBP) is a polymorphic protein that specifically binds to vitamin D and its metabolites. This protein belongs to the albuminoid family and is highly conserved among vertebrates. The gene encoding DBP is mapped to human chromosome 4q11-q13. It is predominantly produced in the liver and is also expressed in the kidney, endocrine pancreatic cells, fat cells, and testis.

애플리케이션

Globulins were used in Biotin/avidin formulations.

생화학적/생리학적 작용

Vitamin D binding protein (DBP) specifically binds and transports vitamin D and its metabolites with high affinity. It promotes fibrillar actin clearance by binding to actin monomers. DBP also binds to unsaturated fatty acids, megalin-cubilin receptor complex, the membrane of leukocytes, and the activation of the complement C5 system. The levels of DBP indicate the free concentration of all vitamin D metabolites. Decreased levels of serum DBP are observed in liver diseases, nephrotic syndrome, malnutrition, severe acute trauma, or disease.

기타 정보

Primarily γ-globulins

물리적 형태

Lyophilized powder containing NaCl

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable