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Merck
모든 사진(1)

Key Documents

G5894

Sigma-Aldrich

Glutaminase from Escherichia coli

Grade VII, lyophilized powder, 500-1,500 units/mg protein

동의어(들):

L-Glutamine amidohydrolase

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About This Item

CAS Number:
효소 위원회 번호:
MDL number:
UNSPSC 코드:
12352204
NACRES:
NA.54

유형

Grade VII

Quality Level

형태

lyophilized powder

특이 활성도

500-1,500 units/mg protein

구성

Protein, ~10% Lowry

저장 온도

−20°C

유사한 제품을 찾으십니까? 방문 제품 비교 안내

생화학적/생리학적 작용

Glutaminase catalyzes the conversion of glutamine to glutamate.

결합

Chromatographically purified from Grade V

단위 정의

One unit will deaminate 1.0 μmole of L-glutamine per min at pH 4.9 at 37 °C.

물리적 형태

Lyophilized powder containing stabilizer and potassium succinate

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Krupa Shukla et al.
Journal of medicinal chemistry, 55(23), 10551-10563 (2012-11-16)
Bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES) is a potent and selective allosteric inhibitor of kidney-type glutaminase (GLS) that has served as a molecular probe to determine the therapeutic potential of GLS inhibition. In an attempt to identify more potent GLS inhibitors with improved
Natalie E Simpson et al.
Epigenetics, 7(12), 1413-1420 (2012-11-03)
The interplay of metabolism and epigenetic regulatory mechanisms has become a focal point for a better understanding of cancer development and progression. In this study, we have acquired data supporting previous observations that demonstrate glutamine metabolism affects histone modifications in
Javier Ampuero et al.
PloS one, 7(11), e49279-e49279 (2012-11-21)
To investigate the influence of metformin use on liver dysfunction and hepatic encephalopathy in a retrospective cohort of diabetic cirrhotic patients. To analyze the impact of metformin on glutaminase activity and ammonia production in vitro. Eighty-two cirrhotic patients with type
L N Ramya et al.
Applied biochemistry and biotechnology, 167(8), 2144-2159 (2012-06-12)
Acute lymphoblastic leukaemia (ALL) is one of the leading types of malignant disorder seen in children. Viral infections, genetic factors and exposure to chemical carcinogens are some of the factors responsible for causing ALL. Treatment strategies followed for curing ALL
Eva M J Peters et al.
The Journal of investigative dermatology, 133(5), 1150-1160 (2012-12-14)
Determining hitherto uninvestigated and safe targets to halt the aging process is important in our aging society. Graying is a hallmark of the aging process and may be used to identify aging tissue for comparative analysis. Here we analyzed differential

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