추천 제품
생물학적 소스
chicken
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
종 반응성
human
제조업체/상표
Genway 15-288-10072F
기술
indirect ELISA: suitable
western blot: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... CRP(1401)
일반 설명
C-reactive protein (CRP) is a member of a protein family that serve as soluble pattern recognition molecules. This protein is generated and liberated in the circulation in response to infection and tissue damage. CRP gene is located on human chromosome 1q23.2.
CRP is synthesized by human peripheral blood mononuclear cells. The CRP gene is localized to chromosome 1.
애플리케이션
Anti-C-Reactive Protein antibody produced in chicken is suitable for western blotting at a working dilution of 1:500 and for cell staining at a working dilution of 1:200. It is also suitable for indirect ELISA.
생화학적/생리학적 작용
C-Reactive Protein (CRP) is a homopentamer that belongs to the pentaxin family. CRP binds to phosphorylcholine in a calcium dependent manner and plays a key role in host defense. It is involved in several defense mechanisms such as, agglutination, bacterial capsular swelling, phagocytosis and complement fixation. CRP interacts with secreted M-ficolin anchored to monocyte transmembrane G protein-coupled receptor 43 and mediates immune signaling and regulates host defense. It scavenges nuclear waste that is released from cells following apoptosis.
C-reactive protein (CRP) plays a major role the early stages of atherosclerosis and pantothenic acid (PA). It shows an antioxidant effect in inflammatory process. The active monomeric form of C-reactive protein (CRP) is involved in proinflammatory functions.
물리적 형태
Solution in phosphate buffered saline containing 0.02% sodium azide.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
가장 최신 버전 중 하나를 선택하세요:
T M Murphy et al.
The Journal of experimental medicine, 173(2), 495-498 (1991-02-01)
We synthesized and cloned cDNA from human peripheral blood mononuclear cell (PBMC) transcripts that were hybrid selected by pCRP5, a liver C-reactive protein (CRP)-specific cDNA (Woo, P.,J.R. Korenberg, and A.S. Whitehead. 1985. J.Biol. Chem. 260:13384). Three hybrid-selected cDNA clones, HScDNA1
The long-term relationship between dietary pantothenic acid (vitamin B5) intake and C-reactive protein concentration in adults aged 40 years and older.
Jung S, et al.
Nutrition, Metabolism, and Cardiovascular Diseases, 27(9), 806-816 (2017)
An intrinsically disordered motif mediates diverse actions of monomeric C-reactive protein.
Li HY, et al.
The Journal of Biological Chemistry, 291(16), 8795-8804 (2016)
A P Osmand et al.
Proceedings of the National Academy of Sciences of the United States of America, 74(2), 739-743 (1977-02-01)
Partial amino acid sequences of rabbit C-reactive protein, a peptide derived from human C-reactive protein by cyanogen bromide cleavage, and the C1t subcomponent of the human complement component C1 have been determined. Extensive sequence homology between these proteins establish their
Maternal serum C-reactive protein concentration and intra-amniotic inflammation in women with preterm prelabor rupture of membranes.
Musilova I, et al.
PLoS ONE, 12(8), e0182731-e0182731 (2017)
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