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Merck
모든 사진(1)

주요 문서

K4769

Sigma-Aldrich

Kojibiose

≥98% (HPLC)

동의어(들):

α-D-Glc-(1→2)-D-Glc, 2-O-α-D-Glucopyranosyl-D-glucose

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About This Item

실험식(Hill 표기법):
C12H22O11
CAS Number:
Molecular Weight:
342.30
MDL number:
UNSPSC 코드:
12352201
PubChem Substance ID:
NACRES:
NA.25

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분석

≥98% (HPLC)

양식

powder

기술

HPLC: suitable

색상

white to off-white

solubility

water: 5 mg/mL, clear, colorless

저장 온도

−20°C

SMILES string

OCC(O)C(O)C(O)C(OC1OC(CO)C(O)C(O)C1O)C=O

InChI

1S/C12H22O11/c13-1-4(16)7(17)8(18)5(2-14)22-12-11(21)10(20)9(19)6(3-15)23-12/h2,4-13,15-21H,1,3H2

InChI key

PZDOWFGHCNHPQD-UHFFFAOYSA-N

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애플리케이션

Kojibiose, a disaccharide product of glucose caramelization and an inhibitor of plant glucosidase I, may be used to help identify and characterize glucosidase I enzymes involved in terminal deglycosylation of high-mannose oligosaccharides.[1] Kojibiose may be used as a substrate to study the biological species, enzymes and catabolic processes that catabolize it as an energy source. Kojibiose may be used to identify, differentiate and characterize kojibiose phosphorylase(s) (KP).[2]

생화학적/생리학적 작용

Kojibiose is an inhibitor of plant glucosidase I. It inhibits the removal of terminal glucose from (Glc)3(Man)9(GlcNAc)2.
Kojibiose is an inhibitor of plant glucosidase I. It inhibits the removal of terminal glucose from the high-mannose oligosaccharide (Glc)3(Man)9(GlcNAc)2, either from the free oligosaccharide or from the oligosaccharide attached to a protein via N-linkage.

기타 정보

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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1 of 2

Satoshi Okada et al.
The FEBS journal, 281(3), 778-786 (2013-11-22)
Glycoside hydrolase (GH) family 65 contains phosphorylases acting on maltose (Glc-α1,4-Glc), kojibiose (Glc-α1,2-Glc), trehalose (Glc-α1,α1,-Glc), and nigerose (Glc-α1,3-Glc). These phosphorylases can efficiently catalyze the reverse reactions with high specificities, and thus can be applied to the practical synthesis of α-glucosyl
Wouter F J Hogendorf et al.
Bioorganic & medicinal chemistry, 18(11), 3668-3678 (2010-04-23)
In this paper the synthesis of an Enterococcus Faecalis teichoic acid (TA) hexamer is presented. The key kojibiosyl-glycerol phosphoramidite building block was obtained by condensation of thioglucose donors, provided with various protecting groups at the C2 hydroxyl function with an
Jong-Hyun Jung et al.
Journal of bacteriology, 196(5), 1122-1131 (2014-01-07)
A unique gene cluster responsible for kojibiose utilization was identified in the genome of Pyrococcus sp. strain ST04. The proteins it encodes hydrolyze kojibiose, a disaccharide product of glucose caramelization, and form glucose-6-phosphate (G6P) in two steps. Heterologous expression of
Jarred Yasuhara-Bell et al.
Microorganisms, 8(3) (2020-03-11)
Rathayibacter toxicus is a Gram-positive, nematode-vectored bacterium that infects several grass species in the family Poaceae. Unique in its genus, R. toxicus has the smallest genome, possesses a complete CRISPR-Cas system, a vancomycin-resistance cassette, produces tunicamycin, a corynetoxin responsible for
S Ogawa et al.
Carbohydrate research, 307(1-2), 83-95 (1998-07-11)
Two kojibiose-type pseudo-disaccharides and a trisaccharide, containing a 5-amino-1,2,3,4-cyclopentanetetrol derivative or valienamine, linked by way of nitrogen bridges to the sugar residues, have been designed and synthesized as processing alpha-glucosidase I inhibitors. Synthesis of the pseudo-disaccharides was carried out starting

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