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애플리케이션
Manganese(II) chloride tetrahydrate has been used:
- as trace element in the fungal complete medium
- as a supplement in the culture medium for cochlear organotypic culture
- to determine its in vivo antiviral activity against herpes simplex virus-1 (HSV-1), vesicular stomatitis virus (VSV) and vaccinia virus in mice
생화학적/생리학적 작용
Manganese is an essential and one of the abundant metal in the tissues of mammals. It plays a key role in the physiological process like development, neuronal function, immune regulation, reproduction, and antioxidant defences. It functions as a cofactor and regulates the activity of the enzymes like oxido-reductases, isomerases, transferases, ligases, lyases and hydrolases It is involved in the innate immunity against viruses.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1 - STOT RE 2
표적 기관
Brain
Storage Class Code
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK
WGK 2
Flash Point (°F)
does not flash
Flash Point (°C)
does not flash
개인 보호 장비
dust mask type N95 (US), Eyeshields, Gloves
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시험 성적서(COA)
이미 열람한 고객
Salidroside protects inner ear hair cells and spiral ganglion neurons from manganese exposure by regulating ROS levels and inhibiting Apoptosis
Toxicology Letters, 310, 51-60 (2019)
manganese Increases the Sensitivity of the cgas-sting Pathway for Double-stranded Dna and Is Required for the Host Defense against Dna Viruses.
Immunity, 48(4), 675-687 (2018)
Toxicology letters, 279, 77-86 (2017-08-06)
Manganese (Mn) is an indispensable cofactor for many enzymes and a basic factor for many reproductive and metabolic pathways. However, exposure to high concentrations of Mn can result in deleterious effects on the central nervous system and peripheral nerves, including
Toxicology letters, 310, 51-60 (2019-04-17)
Manganese (Mn) is an essential cofactor for many enzymes and thus plays an important role in normal growth and development. However, persistent exposure to high Mn concentrations can result in deleterious effects on not only the central nervous system but
Agrobacterium-mediated transformation of the filamentous fungus Aspergillus awamori.
Nature Protocols, 3(10), 1671-1671 (2008)
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