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Merck
모든 사진(1)

주요 문서

N3628

Sigma-Aldrich

4-Nitrophenyl α-L-fuco­pyran­oside

≥98% (TLC), powder

동의어(들):

4-Nitrophenyl alpha-L-fucopyranoside

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About This Item

실험식(Hill 표기법):
C12H15NO7
CAS Number:
Molecular Weight:
285.25
Beilstein:
89535
EC Number:
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:
NACRES:
NA.32

제품명

4-Nitrophenyl α-L-fuco­pyran­oside, ≥98% (TLC)

Quality Level

분석

≥98% (TLC)

양식

powder

solubility

acetone: 4 mg/mL, clear, colorless

저장 온도

−20°C

SMILES string

C[C@@H]1O[C@@H](OCc2ccc(cc2)[N+]([O-])=O)[C@@H](O)[C@H](O)[C@@H]1O

InChI

1S/C13H17NO7/c1-7-10(15)11(16)12(17)13(21-7)20-6-8-2-4-9(5-3-8)14(18)19/h2-5,7,10-13,15-17H,6H2,1H3/t7-,10+,11+,12-,13+/m0/s1

InChI key

DCCILTHSDFBSCK-RCGNDRPLSA-N

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애플리케이션

4-Nitrophenyl α-L-fucopyranoside (αfTM) has been used as a chemical substrate for α-fucosidase to determine carbohydrate-active enzymes (CAZymes) activity. It has also been used as a nitrophenyl-linked substrate in p-nitrophenyl glycoside-based enzyme assays to determine the enzyme activity in cecal samples

생화학적/생리학적 작용

4-Nitrophenyl α-L-fucopyranoside is a chromogenic substrate that is used in kinetic studies of α-fucosidases.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Erik H Klontz et al.
Nature communications, 11(1), 6204-6204 (2020-12-06)
Fucosylation is important for the function of many proteins with biotechnical and medical applications. Alpha-fucosidases comprise a large enzyme family that recognizes fucosylated substrates with diverse α-linkages on these proteins. Lactobacillus casei produces an α-fucosidase, called AlfC, with specificity towards
Alex Steimle et al.
STAR protocols, 2(1), 100326-100326 (2021-03-06)
The gut microbiome expresses a multitude of enzymes degrading polysaccharides in dietary plant fibers and in host-secreted mucus. The quantitative detection of these glycan-degrading enzymes in fecal samples is important to elucidate the functional activity of the microbiome in health
Mahesh S Desai et al.
Cell, 167(5), 1339-1353 (2016-11-20)
Despite the accepted health benefits of consuming dietary fiber, little is known about the mechanisms by which fiber deprivation impacts the gut microbiota and alters disease risk. Using a gnotobiotic mouse model, in which animals were colonized with a synthetic
M H Tomassi et al.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 43(1), 8-12 (2009-12-23)
The manner by which effects of simultaneous mutations combine to change enzymatic activity is not easily predictable because these effects are not always additive in a linear manner. Hence, the characterization of the effects of simultaneous mutations of amino acid
Regioselective synthesis of alpha-L-fucosyl-containing disaccharides by use of alpha-L-fucosidases of various origins.
K Ajisaka et al.
Carbohydrate research, 224, 291-299 (1992-02-07)

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